Disease Information for Acoustic neuroma

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Clinical Manifestations
Signs & Symptoms
Hiccough/Hiccups
Cranial nerve abnormalities/involvement/signs
Dizziness/Dizzy
Facial Nerve Palsy/Facial Paralysis
Facial weakness/droop, unilateral
Nystagmus
Unable to tandem walk/straight line
Vertigo
Vertigo/relentless
Nerve deafness, recent onset
Acute Hearing Loss
Head Movement Vertigo
Head Thrust (Heave) Test Sign
Hearing loss
Hearing problems
Hypesthesia/posterior ear canal (Hitselberger) sign
Pulsatile tinnitus
Referred ear Pain Otalgia
Sound distortion
Sudden deafness
Tinnitus
True Vertigo Sign Confirmed
Unilateral sudden deafness
Vertigo in Children
Vertigo in Elderly
Disease Progression
Course/Chronic disorder
Course/Chronic only
Laboratory Tests
Abnormal Lab Findings (Non Measured)
CSF abnormal
CSF Protein increased/cells absent
Diagnostic Test Results
Other Tests & Procedures
Lumbar puncture/abnormal
TEST/Audiometrics/abnormal
TEST/Audiometrics/Tone decay
TEST/Caloric/nystagmus/challenge abnormal
TEST/Canal paresis/Barany test/abnormal
Electrodiagnosis
EEG/ABR/Auditory evoked response/potential abnormal/AEP
EEG/Auditory evoked potential/unilateral failure
EEG/Evoked Potential Responses Abnormal
Electronystagmography Abnormal
CT Scan
CT Scan/Mass in the middle fossa/Head
CT Scan/Mass, cerebellopontine angle/Head
MRI/Head Brain Abnormal
CT Scan/Acoustic Cochlear Abnormalities
MRI/Acoustic high resolution/cochlea abnormal
X-RAY
Xray/Auditory meatus widened or eroded/Skull
Xray/Petrous ridge or apex erosion/Head
Xray/Destructive mass in middle ear/Head
Associated Diseases & Rule outs
Rule Outs
General paresis/CNS syphilis
Labyrinthitis
Mastoiditis
Meniere's disease
Meningioma
Viral labyrinthitis
General paralysis/General Paresis
Associated Disease & Complications
Acoustic neuroma
Bells palsy/Facial nerve paralysis
Bilateral Acoustic Neuroma syndrome
Deafness
Deafness, sensorineural
Facial nerve palsy/secondary
Stroke/Child
Ataxia Disorder
Facial Paralysis
Deafness Acquired
Disease Mechanism & Classification
Class
CLASS/Brain/CNS disorder (ex)
CLASS/Eighth (auditory) nerve involvement
CLASS/Neurologic (category)
CLASS/Ears/accessory (category)
Pathophysiology
Pathophysiology/Gene locus 22q12
Pathophysiology/Gene locus chromosome 22
Pathophysiology/CNS-Systemic Vertigo
Pathophysiology/Peripheral Vertigo
Process
PROCESS/Neoplastic (category)
PROCESS/Primary intracranial tumor (ex)
Synonyms
Synonym
Acoustic Neurilemmoma, Acoustic Neurilemmomas, Acoustic Neurilemoma, Acoustic Neurilemomas, acoustic neurinoma, Acoustic Neurinomas, Acoustic neuroma, Acoustic neuroma (disorder), Acoustic Neuromas, Acoustic Schwannoma, Acoustic Schwannomas, AN Acoustic neuroma, BRAIN TUMOR ACOUSTIC NEUROMA, INTRACRANIAL NEOPLASM ACOUSTIC NEUROMA, Neurilemmoma Acoustic, Neurilemmomas Acoustic, Neurilemoma Acoustic, Neurilemomas Acoustic, NEURINOMA ACOUSTIC, Neurinomas Acoustic, NEUROFIBROMA ACOUSTIC, Neuroma acoustic, NEUROMA ACOUSTIC, Neuromas Acoustic, Schwannoma Acoustic, Schwannoma Vestibular, Schwannomas Acoustic, Schwannomas Vestibular, Vestibular Neurilemmoma, Vestibular schwannoma, Vestibular Schwannomas, Synonym/Acoustic neurinoma, Synonym/Acoustic neurofibroma, Synonym/Perineural fibroblastoma
Definition

A schwannoma that arises from the vestibular division of the vestibulocochlear nerve and tends to present in the fifth or sixth decade of life; Clinical manifestations include loss of hearing, headache, vertigo, facial pain, tinnitus, and facial weakness; Bilateral acoustic neuromas are associated with NEUROFIBROMATOSIS 2-------- (From Adams et al, Principles of Neurology, 6th ed,)------------------------------- Lesions of the eighth cranial nerve and central audiovestibular pathways produce neural hearing loss and vertigo; One characteristic of neural hearing loss is deterioration of speech discrimination out of proportion to the decrease in pure tone thresholds; Another is auditory adaptation, wherein a steady tone appears to the listener to decay and eventually disappear; Auditory evoked responses are useful in distinguishing cochlear from neural losses and may give insight into the site of lesions within the central pathways; The evaluation of central audiovestibular disorders usually requires imaging of the internal auditory canal, cerebellopontine angle, and brain with enhanced MRI;-----------------------------------------------------------Vestibular Schwannoma (Acoustic Neuroma); Eighth nerve schwannomas are among the most common of intracranial tumors; These benign lesions arise within the internal auditory canal and gradually grow to involve the cerebellopontine angle, eventually compressing the pons and resulting in hydrocephalus; Their typical auditory symptoms are unilateral hearing loss with a deterioration of speech discrimination exceeding that predicted by the degree of pure tone loss; Nonclassic presentations, such as sudden unilateral hearing loss, are fairly common; Any individual with a unilateral or asymmetric sensorineural hearing loss should be evaluated for an intracranial mass lesion; Vestibular dysfunction more often takes the form of continuous dysequilibrium than episodic vertigo; Other lesions of the cerebellopontine angle such as meningioma and epidermoids may have similar audiovestibular manifestations; Diagnosis is made by enhanced MRI, though auditory evoked responses may have a role in screening; Microsurgical excision is most often indicated, though small tumors in older individuals may be managed with stereotactic radiotherapy or simply followed with serial imaging studies; [CURRENT dx rx 2005]-------------------------------------Acoustic Neuroma

Acoustic Neurilemoma; Bilateral Acoustic Neuroma

Cerebellopontine Angle Tumor; Fibroblastoma, Perineural;

Neurinoma of the Acoustic Nerve; Neurofibroma of the Acoustic Nerve; Schwannoma of the Acoustic Nerve; Acoustic Neuroma is a benign (non-cancerous) growth that begins at the 8th cranial nerve, which runs from the brain to the inner ear; Any disruption of the signals sent along the 8th cranial nerve will interfere with hearing and with the patient’s balance--------[NORD 2005]--------------

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Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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