Disease Comparison Results (show differences mode) for Paroxysmal Nocturnal Hemoglobinuria and Renal Failure Acute

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Renal Failure Acute

Found: 196 | Differences: 187

Paroxysmal Nocturnal Hemoglobinuria

Found: 214 | Differences: 205

Paroxysmal Nocturnal Hemoglobinuria and Renal Failure Acute sharing 8 common findings. (show all, show common, show differences)

Clinical Manifestations
Signs & Symptoms
Edema Children
Facial edema/swelling
Diastolic hypertension
Fluid retention/Mild edema
High blood pressure/sign
Tachycardia/Fast heart rate
Beau's lines/Mees lines fingernails
Bruising/Ecchymosis
Nail Striations
Petechiae/Petechial rash
Pruritis Itching
Excessive/easy bruising tendency
Anorexia Decreased appetite
Hiccough/Hiccups
Nausea
Vomiting
Breath odor of Ammonia
Characteristic breath odor
Dry mouth/Mucous membranes
Metallic taste
Liver flap tremor/Asterixis
Chvostek's sign
Cramping in Extremities
Muscle fasciculations
Muscle twitches
Muscle weakness
Twitchy/muscle spasms
Weak/Weak as a kitten (symptom)
Altered Mental State Diabetic
Altered mental status Mental status change
Confusion/agitation on exam
Confusion/Disoriented
Fatigability
Infant Seizures
Lethargy/torpor
Myoclonus/Myoclonic jerks on exam
Obtunded/poorly responsive status/signs
Seizures
Seizures/Children/recurrent
Stupor/poor reponse to stimulus
Sudden unconsciousness
Weakness/Diffuse motor loss
Hyperpnea
Rapid Breathing
Tachypnea/Increased respiratory rate
Chronic Back Pain
Epistaxis, severe/persistent
Anuria
Breath odor of Stale fish
Oliguria/Decreased urine output
Oliguria/sudden
Uremic fetor
Acutely ill patient/signs
Chronic Fatigue
Enervated/extreme acute fatigue
Fatigue Tiredness Exhaustion
Neonatal edema/anasarca
Weakness
Weakness non-neuromuscular/systemic
Weight gain
Weight Loss
Eyelid Fasciculations
Retinopathy signs on exam
Clinical Presentation & Variations
Presentation/Hypertension Abrupt Onset
Presentation/Diabetic Decreased need for Insulin
Disease Progression
Course/Acute
Course/Acute only
Course/Potentially lethal/untreated
Lethal Potential
Demographics & Risk Factors
Established Disease Population
Patient/Bacterial endocarditis
Patient/Preeclampsia/toxemia
Patient/Shock status
Patient/Severe/extensive Burns
Patient/Glomerulonephritis, acute
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Osmotic gap (low Na/high osmolality) (Lab)
Renal function abnormalities (Lab)
Abnormal Lab Findings - Decreased
Aspartamine aminotransferase (SGOT, AST) (Lab)
Bicarbonate, serum (Lab)
Calcium, serum (Lab)
Carbon Dioxide Total Content/CO2
Creatine clearance (Lab)
Lymphocytes (Lab)
PCO2, arterial blood (Lab)
pH, arterial blood (Lab)
Sodium, serum (Lab)
URINE Osmololality
URINE Potassium
Abnormal Lab Findings - Increased
Acute lymphopenia/transient
Brain Natiuretic Peptide/BNP level (Lab)
BUN/Blood urea nitrogen (Lab)
Creatinine, serum (Lab)
Digoxin serum level (Lab)
Fibrin Degredation Product (FDP) (Lab)
Fibrin Split Products/FSP/Dimers/Monomers (Lab)
Fibrinopeptide A
FibrinPeptide A
Free fatty acids/FFA/Non-esterified (Lab)
Gastrin, serum (Lab)
Glucagon (Lab)
Growth hormone/STH, plasma (Lab)
Lactic acid/Lactate (Lab)
Lipase (Lab)
Magnesium (Lab)
NT-proBNP indicator levels (N-terminal)
Phosphate Serum (Lab)
Potassium, serum (Lab)
Prolactin (Lab)
Sodium, serum (Lab)
Sulfate, serum (Lab)
Triglyceride lipase (Lab)
Uric acid, serum (Lab)
URINE Glucuronidase, beta
URINE Growth hormone
URINE Hexosaminidase
URINE Protein (Albumin)
Diagnostic Test Results
Isotope Scan
Isotope/DMAS Kidney Scan Abnormal
EKG (ECG)
EKG/Prolonged QT interval (ECG)
EKG/Prolonged QT/Peaked T Waves (ECG)
X-RAY
Xray/Chest abnormal
Xray/Congestive heart failure signs/Chest
Xray/Chest/Lung fields/Abnormal
Xray/Lung consolidation/Chest
X-RAY With contrast
IVP/Decreased dye visualization/bilateral
IVP/Dense nephrogram, bilateral
Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs
Hyperkalemic periodic paralysis
Myxedema coma
Associated Disease & Complications - Causes
Acidosis
Acidosis, metabolic
Acute anuria/renal failure
Azotemia in Children
Azotemia in Elderly
Azotemia/Acute
Congestive heart failure
Convulsions (grand mal)
Death Outcome
Digitalis toxicity/poisoning
Gastrointestinal bleeding
Hallucinations
Hyperkalemia
Hypermagnesemia
Hypernatremia
Hyperphosphatemia
Hypertension
Hyperuricemia
Hypervolemia
Hypocalcemia
Hypocapnea/hypocarbia
Hyponatremia
Intravenous pyelogram CONTRA-INDICATED/DANGER
Lactic acidosis
Lymphocytopenia
Metabolic Acidosis with High Anion Gap
Metabolic encephalopathy
Pneumonia, pneumococcal
Pneumonia, staphylococcus
Potassium administration/effect/toxicity
Proteinuria
Retinopathy
Sideroblastic Anemia Sideroachrestic
Xerostomia
Hypergastrinemia
Disease Synergy
Synergy/Digitalis/digoxin toxicity
Synergy/On medications/medication
Synergy/Salt load/high sodium diet
Disease Mechanism & Classification
Class
CLASS/Renal/kidney involvement/disorder (ex)
CLASS/Urologic (category)
Pathophysiology
Pathophysiology/Blood volume/increase/high
Pathophysiology/Alveolar consolidation
Pathophysiology/Decreased glomerular filtration
Pathophysiology/Salt/water retention, renal
Process
PROCESS/Complicating disorder (ex)
PROCESS/Non-hereditary metabolic disorder (ex)
Synonyms
Synonym
Synonym/ARF
Synonym/Azotemia
Treatment
Drug Therapy - Contraindication
RX/Diuretic
RX/Magnesium oxide
RX/Potassium-sparing diuretic
Other Treatments
TX/Dialysis.
TX/Fluid restriction
TX/Medical emergency
Clinical Manifestations
Signs & Symptoms
Paroxysmal Shivering
Rigors/Shaking chills
Teeth Chattering
Uncontrollable Shaking
Abdominal pain Radiates to Back
Recurrent Abdominal Pain
Stroke Syndrome Child
Mid-back pain
AM dark urine/on awakening
Coca-Cola dark (coffee colored) urine
Costovertebral Angle Pain/Tenderness
Dark urine
Flank Pain
URINE Color Red
Massive splenomegaly
Splenomegaly
Chills
Nocturnal awakenings Events Phenomenon
Otherwise well Isolated problem
Pallor
Clinical Presentation & Variations
Presentation/Deep Vein Thrombosis Young Recurrent
Presentation/Anemia Refractory
Presentation/Refractory iron deficiency anemia
Disease Progression
Course/Attacks Episodic Spells
Course/Chronic disease crisis/flare/attacks
Course/Chronic disorder
Course/Chronic only
Course/Episodes last 1 to 3 weeks/remit recur months later
Course/Paroxysmal
Course/Periodic Episodic
Course/Prognosis bad/usually
Pancytopenia with Hypercellular Marrow
Pancytopenia with Normal Marrow
Demographics & Risk Factors
Population Group
Child
Population/Pediatrics population
Family History
Family history/Anemia
Sex & Age Groups
Population/Adult ('twenties')
Population/Adult Aged Only
Population/Adult/all
Population/Child
Population/Children/all
Population/Male
Laboratory Tests
Microbiology & Serology Findings
Reticulocytosis
Abnormal Lab Findings (Non Measured)
Cytogenetics Abnormal
Acid hemolysis test (Ham) positive (Lab)
Chromosomal abnormality (Lab)
Coombs negative hemolytic anemia (Lab)
Flow cytometry tests/abnormal (Lab)
Flow Cytometry/CD55 and CD59 defects (Lab)
Indirect bilirubin inc/normal direct bil. (Lab)
Leukopenia
Microcytes/small RBCs on Blood smear
Microcytosis/microcytic anemia (Lab)
Normocytic anemia
Normocytic Anemia/High Retic count
Normocytic/Normochromic Anemia (Lab)
PI-linked Antigen (Cd14/CD59) positive
Sucrose-water hemolysis test/abnormal (Lab)
URINE Color Brown
URINE Dipstick /Blood abnormal
Abnormal Lab Findings - Decreased
Ferritin, serum (Lab)
Hematocrit (Lab)
Hemoglobin (Lab)
Iron, serum (Lab)
Leukocyte Alkaline phosphatase (Lab)
MCV/Mean Corpuscular Volume (Lab)
Platelet survival (Lab)
RBC/Red Blood Count (Lab)
Abnormal Lab Findings - Increased
Bilirubin, serum (Lab)
C3, serum (Lab)
Fetal hemoglobin (Lab)
Free hemoglobin, plasma (Lab)
Indirect bilirubin (Lab)
Lactic Dehydrogenase (LDH LH) (Lab)
Leukocyte Alkaline phosphatase (Lab)
Methemalbumin (Lab)
Osmotic fragility, RBC (Lab)
Platelet Antibody Detection
Polychrome RBCs (Lab)
RBC Actylcholinesterase level (Lab)
Reticulocytes (Lab)
Spherocytes (Lab)
TIBC/Total Iron Binding capacity (Lab)
URINE Hemoglobin
URINE Hemosiderin
URINE Red blood cells
URINE Urobilinogen
STOOL Urobilinogen
Diagnostic Test Results
Pathology
Bone Marrow/Erythroid hyperplasia
Bone Marrow/Hypercellular
Bone Marrow/Normoblasts hyperplasia
BX/Renal hemosiderosis
PATH/Erythrophagocytosis/Spleen
Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs
Hemolytic anemia/autoimmune
Myelodysplasia
Associated Disease & Complications - Causes
Acute Myelogenous/Myeloblastic Leukemia AML
Acute Tubular Necrosis
Anemia
Anemia, aplastic
Anemia, severe
Arterial Occlusion
Bilirubinemia
Bone Marrow Fibrosis
Brisk Hemolysis/Active
Cavernous sinus thrombosis
Cerebral thrombosis
Cerebral vein thrombosis/phlebitis
Cholelithiasis
Disseminated intravascular coagulation
Folic acid deficiency anemia
Hemoglobinuria
Hemolysis anemia/acute/active
Hepatic vein thrombosis (Budd-Chiari)
Hypercoagulability/Thrombophilia
Iron deficiency anemia
Leukemia
Mesenteric vein thrombosis
Myelodysplasia
Myelofibrosis
Myelofibrosis secondary
Pancytopenia
Paroxysmal nocturnal hemoglobinuria
Phlegmasia cerulea dolens
Portal vein thrombosis
Priapism/persistent erection
Pulmonary embolism
Pulmonary infarction
Purpura fulminans
Raynaud's syndrome
Renal Failure Chronic
Stroke/Child
Thrombocytopenia
Thrombocytopenia in Children
Thrombocytopenia in Elderly
Thromboembolic disease
Thrombophlebitis Arm/Deep Vein
Thrombophlebitis, deep vein
Thrombosis, arterial
Thrombosis, renal vein
Phlebitis, recurrent
Hypercoaguability
Disease Synergy
Synergy/Immunizations/vaccinations
Synergy/Infection
Synergy/Iron ingestion/administration
Synergy/Menses trigger
Disease Mechanism & Classification
Class
CLASS/Primary organ/system disorder (ex)
CLASS/Erythrocyte disorder (ex)
CLASS/Hematologic (category)
CLASS/Stem cell disease (ex)
Pathophysiology
Pathophysiology/Chromosome gene/segment deletion (ex)
Pathophysiology/Gene locus Chromosome X.
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Gene locus PIG-A gene /X-chromosome
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Arterial Occlusion
Pathophysiology/Thrombosis veins lower ext/iliac/femoral
Pathohysiology/PIGA defect/GPI Membrane Anchor fails
Pathophysiology/Chronic Iron loss
Pathophysiology/Complement sensitivity
Pathophysiology/Erythrocyte membrane disorder
Pathophysiology/Hemolysis
Pathophysiology/Hemolytic process/effect
Pathophysiology/Intrinsic CO production increased
Pathophysiology/Myelodysplasia process
Pathophysiology/Non-immune hemolytic anemia
Pathophysiology/Plasma c3b inactivatior/failure
Pathophysiology/RBC membrane defect/complement risk
Pathophysiology/RBC membrane glycosyl-phosphatidyl-inositol path
Pathophysiology/RBC membrane/Missing key proteins
Pathophysiology/Stem cell defect
Pathophysiology/Unusual sensitive RBC to C3 in plasma
Pathophysiology/Complement activation
Pathophysiology/Granulocyte lyses/manifestation
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Episodic disorder (ex)
PROCESS/Hereditofamilial (category)
PROCESS/Idiopathic/unclassified/unknown (category)
PROCESS/INCIDENCE/Acquired disorder
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Pre-Leukemic condition (ex)
PROCESS/Coagulation derangement/disorder (ex)
PROCESS/Somatic mutation/not hereditary
Synonyms
Synonym
Synonym/Marchiafava-Micheli syndrome
Synonym/PNH
Treatment
Drug Therapy - Contraindication
RX/Oral contraceptive
Drug Therapy - Indication
RX/Blood transfusion/packed cells
RX/Eculizamab (Soliris)
RX/Folic/Folinic acid (Leukovorin)
RX/Iron/Ferrous Sulfate (Feosol)
RX/Prednisone (Deltasone)
SX/Bone marrow transplant
SX/Stem cell transplant/allogenic
SX/Stem-cell transplant
Other Treatments
TX/Platelet transfusion
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