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Disease Comparison Results (show all mode) for Multiple Sclerosis and Myasthenia gravis

Clinical
Demographics
Lab
Diagnostic
Diseases
Classification
Synonyms
Treatment
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Myasthenia gravis

Found: 372 | Differences: 289

Multiple Sclerosis

Found: 452 | Differences: 370

Multiple Sclerosis and Myasthenia gravis sharing 77 common findings. (show all, show common, show differences)

Clinical Manifestations
Signs & Symptoms: Facial Nerve Palsy/Facial Paralysis; Facial weakness/droop, unilateral
Signs & Symptoms: Hyperextensable Joints Infant; Vertical Diplopia; Myopathic facies/snarling smile; Transverse smile; Appetite increased; Choking; Dysphagia for solids; Dysphagia Liquids; Dysphagia Swallowing Difficulties; Polyphagia; Regurgitation; Chewing problems; Decreased taste ability/Hypoguesia; Jaw Claudication; Pharyngeal cordination problems; Slack jaw/inability to close mouth; Tongue Protrudes Infant; Weak tongue protrusion; Acute Motor Weakness; Arm/shoulder weakness (symptom); Bilateral Shoulder Muscle pain/Weakness; Central hypotonia, infants; Cranial nerve distribution/muscle weakness; Delay Sitting Unsupported Infant; Distal leg weakness; Distal Muscle Weakness; Episodic muscle weakness; Flaccid jaw; Head Lag Infant Sign; Hypotonia; Masseter muscle weakness; Mouth Hangs Open Infant; Muscle weakness; Muscle weakness/with repetitive challenge; Muscles Soft/Doughy Infant; Myasthenia muscle challenge abnormality/sign; Neck weakness/head nodding; Prolonged Effect NM Blocking Agents; Proximal lower extremity weakness; Proximal muscle weakness; Proximal upper extremity weakness; Rolling Over Delay Infant; Symmetrical muscle involvement/stiffness; Temporal muscle weakness; Weak hand grip; Weak/Weak as a kitten (symptom); Weakness, pharyngeal muscles/signs; Areflexia; Babkin infant sign/Abnormal; Bilateral abdominal reflex decreased; Chronic progressive ophthalmoplegia/Bilateral/CPEO; Conjugate gaze paralysis; Cranial nerve abnormalities/involvement/signs; Deep tendon reflexes normal; Delayed walking milestone/child; Development Motor Skills (Milestones) Delayed; Dysarthria; Facial weakness/droop, unilateral; Fatigability; Flaccid muscle paralysis; Gait disturbance/abnormality; Galant Infant reflex/Abnormal; Grip strength decreased; Head Neck Floppy Infant Hypotonia Sign; Hot bath worsens neurologic symp/signs; Hung reflexes (prolonged relaxation)/Woltman sign; Hyporeflexia/DTRs decreased; Infant Head Support Delay; Jaw jerk decreased; Level of alertness maintained; Loss of Taste; Moro reflex Poor/Absent Infant; Nasal speech/regurgitation; Palmar Grasp infant Reflex Abnormal; Paralysis; Poor head control/infant; Primitive infant reflexes/Abnormal; Rooting infant sign/Abnormal; Slow speech; Slurred speech; Slurred Speech/Acute; Slurred speech/Chronic; Swimming infant reflex/Abnormal; Tonic Neck Infant reflex/Abnormal; Uhthoff phenomenon Heat-trigger Weakness; Weakness/Diffuse motor loss; Apnea In Children; Dyspnea; Respiratory excursions decreased; Shallow breathing; Shallow Breathing Infant; Shortness of breath/SOB; Sudden onset dyspnea; Hysterical status; Difficulty Talking; Dysphonia; Garbled/nasal sounding voice; Hoarseness; Nasal/Hyponasal sound to voice; Pooling saliva pharynx/sign; Voice Alteration; Voice Alteration in Elderly; Voice change/disturbance/Unusual; Voice/phonation problems; Chronic Fatigue; Decreased exercise tolerance/effort fatigue; Difficulty lifting heavy items; Enervated/extreme acute fatigue; Fatigue; Fatigue Tiredness Exhaustion; Fatigue Tiredness in Elderly; Poor Stamina; Weakness; Weakness, Gradual Onset; Blurred Cloudy Vision; Difficulty Closing Eyelids; Difficulty Focusing Eyes; Dimming vision/acute; Diplopia Double vision; Double Image Vision Confirmed; Dry eyes/poor tearing; Dryness Conjunctiva; Eye symptoms/signs; Eyelid Retraction; Eyelid twitching/gaze elevation; Grainy/Gritty Eye Sensation; Inspissated secretions/mucus eye; Lid Lag; Ptosis (blepharoptosis); Ptosis, unilateral (blepharoptosis); Unable to Sustain Gaze; Unable to sustain upward gaze; Upward gaze paralysis/sign; Upward gaze paralysis/voluntary; Visual symptoms; V-phoria eye signs/weak upper gaze diplo.; Weak lid-closure ability; Weak upward/inward gaze
Clinical Presentation & Variations: Presentation/Muscle Weakness Young Woman Facial; Presentation/Muscle weakness Old man Facial area
Disease Progression: Course/Chronic disease crisis/flare/attacks; Course/Chronic disorder; Course/Chronic only; Course/Exacerbation/remission; Course/Postpartum Improvement; Course/Progressive/slowly chronic illness; Onset/gradual; Onset/in third decade; Onset/insidious; Onset/seventh decade

Demographics & Risk Factors
Past History: Past history/Recent URI; Past history/Thymoma; Past history/Thyroidectomy
Established Disease Population: Patient/Lupus erythematosis, systemic; Patient/Penicillamine treated; Patient/Graves disease/thyrotoxicosis; Patient/Myasthenia gravis/on treatment; Patient/Postpartum status; Patient/Pregnant; Patient/Premenstrual status; Patient/Rheumatoid arthritis
Population Group: Middle Age Adult; Woman; Young Adult
Sex & Age Groups: Population/Adult ('twenties'); Population/Adult Aged Only; Population/Adult/all; Population/Female; Population/Fifties adult; Population/Middle-aged adult; Population/Seventies Adult; Population/Sixties-adult; Population/Twenties-Adult/female; Population/Woman patient; Population/Young adult

Laboratory Tests
Abnormal Lab Findings (Non Measured): Chronic lymphopenia; HLA A1 (Lab); HLA A10 (Lab); HLA A3 (Lab); HLA B12 (Lab); HLA B27 (Lab); HLA B7 (Lab); HLA B8 (Lab); HLA DR3 (Lab); HLA DRw2 (Lab); HLA DRw3 (Lab); HLA Dw3 (Lab); HLA Specific association (Lab)
Abnormal Lab Findings - Decreased: Lymphocytes (Lab); pO2, arterial blood (Lab)
Abnormal Lab Findings - Increased: Anti-AcetylCholine receptor antibody/ACh (Lab); Anti-mitochondrial antibodies/AMA (Lab); Anti-MuSK antibodies (Muscle specific tyrosine kinase); Anti-parietal cell antibody (Lab); Anti-skeletal muscle antibody/Anti-striated muscle antibody (Lab); Anti-Striation/Muscle antibodies (labs); Antithyroglobulin antibodies (Lab); Anti-VGCC presynaptic channels; Acute lymphopenia/transient; ANA/Antinuclear antibody/Fluorescent ANA (Lab); Anti-Nuclear Antibody (ANA); Carbon Dioxide Total Content/CO2; MCH (Lab); PCO2, arterial blood (Lab); URINE Catecholamines; URINE Creatine; URINE Metanephrines

Diagnostic Test Results
Other Tests & Procedures: TEST/Tensilon test positive; TEST/Neostigmine test positive; PFT/Vital capacity decreased
Pathology: BX/Muscle/Immune complex on MG end-plate/cryostat; PATH/Thymic hyperplasia; PATH/Thymus/Germinal center hyperplasia
Electrodiagnosis: EMG/Abnormal findings; EMG/Decrementing responses/2-3 HZ stim; EMG/Marked variability motor unit potentials/shape; EMG/Post-tetanic fasciculation; EMG/Rapid decrease evoked potential/on stimulation; Nerve Conduction Study Abnormal ENG; Pulse oximetry/low O2 saturation
CT Scan: CT Scan/Mediastinal/anterior mass/Chest; CT Scan/Thymic enlargement/mass/Chest
X-RAY: Xray/Chest abnormal; Xray/Chest/Lung fields/Abnormal; Xray/Mediastinal/anterior mass/Chest; Xray/Superior sulcus mass/Chest
X-RAY With contrast: Barium Swallowing Cine Abnormality; UGI/Esophagus motility disorder; UGI/Esophagus tertiary contractions; UGI/Hypopharynx/pooled barium vallecula

Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs: Aminoglycoside neuromuscular blockade; Anxiety disorder/panic attacks; Bells palsy/Facial nerve paralysis; Botulism; Carcinomatous myopathy; Carcinomatous neuromuscular syndrome; Carcinomatous neuropathic syndrome; Carpal tunnel syndrome; Chronic fatique syndrome (adult 'mono'); Combined system disease/B12 deficiency; Cranial nerve palsy; Dermatomyositis; Eaton-Lambert syndrome; Familial/infantile myasthenia; Fibromyositis/fibromyalgia syndrome; Guillain-Barre syndrome; Hypokalemic periodic paralysis; Mitochondrial myopathy; Multiple sclerosis; Muscular dystrophy; Myopathy/secondary/nonspecific; Myositis, inclusion body; Myotonia atrophica; Oculopharyngeal muscular dystrophy; Ophthalmoplegia; Organo-phosphate pesticide poisoning; Periodic paralysis syndrome; Periodic paralysis, familial; Polymyalgia rheumatica; Polymyositis; Thyrotoxic ophthalmopathy; Thyrotoxic periodic paralysis; Facial Paralysis
Associated Disease & Complications - Causes: Acidosis, respiratory; Acute respiratory failure/Respiratory arrest; Alveolar hypoventilation/extrapulmonary; Aminoglycoside neuromuscular blockade; Aspiration; Autoimmune disease; Bilateral facial paralysis; Cardiomyopathy, secondary; Curariform drug toxicity; Esophageal motility disorder; Esotropia; Hyperthyroidism (Graves disease); Hypothyroidism (myxedema); Hypoventilation, alveolar; Hypoxemia; Hypoxia, systemic; Lymphocytopenia; Myasthenia gravis; Neonatal Hypotonia/Floppy Baby Syndrome; Ophthalmoplegia; Pneumonia, aspiration; Pneumonia/Bronchopneumonia; Respiratory muscle paralysis; Rheumatoid arthritis; Sjogren's sicca syndrome; Succinylcholine toxicity; Thymoma; Vertical squint/strabismus; Xerophthalmia; Torticollis; Parinaud's Ophthalmoplegia; Chronic Respiratory Acidosis; Continued Hypercapnea
Disease Synergy: Risk factor/Alcohol ingestion; Synergy/Bacitracin medication/application; Synergy/Barbiturates/Chronic RX; Synergy/Colistin medication; Synergy/Environmental extremes/temperature; Synergy/Kanamycin medication; Synergy/Menses trigger; Synergy/Neomycin administration; Synergy/Polymyxin administration; Synergy/Pregnancy; Synergy/Procainamide administration; Synergy/Quinidine medication; Synergy/Streptomycin trigger

Disease Mechanism & Classification
Class: CLASS/Motor neuron/unit disorder (ex); CLASS/Motor-end plate disorder (ex); CLASS/Muscle/tendon/extremities (category); CLASS/Neurologic (category); CLASS/Extraocular muscle involvement/disorder (ex)
Pathophysiology: Pathophysiology/Cytokine gene polymorphism; Pathophysiology/Gene locus 11p11.2-p11.1; Pathophysiology/Gene locus 17p12-p11; Pathophysiology/Gene locus 17p13-p12; Pathophysiology/Gene locus Chromosome 17; Pathophysiology/Gene Locus Identified/OMIM database; Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations); Pathophysiology/Humoral autoantibody; Pathophysiology/IGM mediated/autoimmune; Pathophysiology/Acetyl-choline-recep/defect (NM junct); Pathophysiology/Neuromuscular end-plate disorder (ex); Pathophysiology/Nicotine cholinergic receptor disorder; Pathophysiology/Lung Hypoventilation; Pathophysiology/Lung Ventilation Mechanics; Pathophysiology/Lung Ventilation Neuromuscular
Process: PROCESS/Allergy/collagen/autoimmune (category); PROCESS/Autoimmune disorder (ex); PROCESS/Bimodal age distribution/incidence; PROCESS/INCIDENCE/Rare disease (ex); PROCESS/Osserman disease classification applied; PROCESS/Paraneoplastic neurologic disorder; PROCESS/Vegetative-Autonomic/Endocrine (category)
Toxin: TOXIN/Neurotoxin effect

Synonyms
Synonym: Synonym/Dysthyrotic ocular disorder
Synonym: Synonym/Subset/Neonatal myasthenia; Synonym/Subset/Ocular myasthenia

Treatment
Drug Therapy - Contraindication: RX/Aminoglycoside; RX/Beta-blocker; RX/Doxycycline; RX/Lidocaine (Xylocaine); RX/Magnesium injection; RX/Magnesium sulfate/bolus infusion; RX/Procainamide (Pronestyl); RX/Quinidine (Quinaglute); RX/Tetracycline (Achromycin)
Drug Therapy - Indication: RX/Azathioprine (Imuran); RX/Ciclosporine Cyclosporin (Sandimmune); RX/Corticosteroid (Cortisone); RX/Cyclophosphamide (Cytoxan); RX/Gamma globulin (intravenous, high dose); RX/Immune-suppression; RX/Mycophenolate mofetil (MMF); RX/Neostigmine (Prostigmine); RX/Prednisone (Deltasone); RX/Pyridostigmine (Mestinon); SX/Thymectomy
Other Treatments: TX/Plasmapheresis/exchange.; TX/Ventilation Assist IPPB

Clinical Manifestations
Signs & Symptoms: Face Pain; Numbness of face; Anesthetic area/skin; Anorgasmic male; Loss of libido,male; Retrograde ejaculation; Sexual dysfunction; Anal sphincter/loss of tone/reflex; Bowel/Stool Incontinence; Bowel/stool incontinence in Children; Dysphagia Swallowing Difficulties; Problems with defecation; Decreased taste ability/Hypoguesia; Numbness of tongue; Acute Motor Weakness; Hypertonia; Twitchy/muscle spasms; Unilateral arm symptoms; Unilateral Leg Weakness; Weak/Weak as a kitten (symptom); Weakness, legs, bilateral; Weakness/one arm; Abdominal reflex decreased; Abdominal reflex increased; Abnormal movements/involuntary; Active reflexes; Acute ataxia; Altered mental status Mental status change; Ankle reflexes increased; Aphasia; Arm vibratory sense decreased; Ataxia; Ataxia/Posterior columns; Attacks, neurologic, recurrent, varied; Babinski's up-going toe reflex/unilateral; Babinski's upgoing toes/bilateral; Behavior problems; Bilateral abdominal reflex decreased; Central Facial Paralysis; Cerebellar signs; Clonus; Clonus/bilateral ankle (sustained); Clumsiness/poor coordination; CNS symptoms/signs; Cognitive defect; Confusion/agitation on exam; Confusion/Disoriented; Conjugate gaze paralysis; Coordination/signs; Cranial nerve abnormalities/involvement/signs; Daytime Sleepiness; Delirium; Dizziness/Dizzy; Double vison after vigorous exercise; Dropping things; Dysarthria; Dysconjugate gaze; Dysdiadochokinesia/Alternating failure; Dysesthesias; Dysphasia; Equinus Posture/Ankles; Extinction parietal/sensory two touch sign; Facial Nerve Palsy/Facial Paralysis; Facial weakness/droop, unilateral; Fatigability; Fine-motor coordination problems; Finger to nose test abnormality; Focal neurologic deficit; Gait disturbance/abnormality; Hand paralysis; Handwriting progressive decline; Hemianesthesia; Hemianopsia/homonymous/sign; Hemiplegic Gait; Hemisensory defects; Hot bath worsens neurologic symp/signs; Hyperreflexia/DTRs increased; Impaired judgement/signs; Inattention; Leg reflexes increased; Legs increased resistance/passive stretch; Legs increased tone/spastic/hyperreflexic; Lhermittes sign (tingling on neck flex); Limb weakness/signs; Long tract signs; Loss of Taste; Monoplegia, arm; Monoplegia, leg; Multifocal neurologic deficit/signs; Multiple paralysis/multiplegia, assymetric; Neurologic manifestations/signs; Neurological symptoms/signs; Numbness one hand; Numbness/one-sided; Nystagmus; Nystagmus, Monocular; Nystagmus, pendular; Nystagmus, rotary; Paralysis; Paraparesis in Elderly; Paresthesias; Pathophysiology/Rubral tremor; Position sense decreased/proprioception; Position sense decreased/proprioception Legs; Pyramidal tract signs; Saccard induced nystagmus/squint/latent ophthalmoplegia; Scanning speech; Segmental hypesthesia; Segmental/areflexia upper extremity; Sensory Ataxia; Sensory defects/lower extremities; Sensory loss/lower body/cord level; Slow speech; Slurred speech; Slurred speech/Chronic; Spastic paralysis/signs; Spasticity/Spastic gait; Speech Locution Problems; Spinal cord level lesion/signs; Staggering Gait; Steppage gait; Stroke syndrome/signs; Sudden unconsciousness; Transient limb paralysis/palsy; Tremor; Tremor in Elderly; Tremor,coarse; Uhthoff phenomenon Heat-trigger Weakness; Unable to tandem walk/straight line; Unable to walk; Unusual patterns/sensory loss; Vertical nystagmus; Vertigo; Vibratory sense decreased; Vibratory sense decreased Legs; Weak lower extremities; Weakness/Diffuse motor loss; Anorgasmia/Orgasm Dysfunction; Anorgasmic Female; Vaginal hypesthesia or anhedonism; Affect gay/happy inappropriate; Depressed/discouraged/sad; Destructive Behavior; Dysphoria; Emotional/affective lability; Euphoria/Elated/'high' behavior/Gaiety; Hallucination/visual; Psychiatric manifestations/problems/difficulties; Acute Back Pain; Back Pain; Backache; Chronic Back Pain; Limp; Non-localized shoulder area pain; Anosmia/Loss of sense of smell; Decreased sense of smell; Difficulty Talking; Voice Alteration; Voice Alteration in Elderly; Voice change/disturbance/Unusual; Overflow incontinence; Urinary Incontinence in Elderly; Urine Incontinence; Urine Retention Signs; Balance problems; Chronic Fatigue; Chronically ill patient/signs; Enervated/extreme acute fatigue; Episodic symptoms/events; Falling; Fatigue; Fatigue Tiredness Exhaustion; Heat intolerance/Warm all the time; Walking difficulties; Weakness; Weakness non-neuromuscular/systemic; Acute Vision Loss; Amaurosis fugats/transient blindness-vision loss; Anisocoria; Bilateral Vision Loss; Blindness/sudden/unilateral; Blindness/unilateral; Blurred Cloudy Vision; Central Vision Loss/Scotoma; Chronic Progressive Vision Loss; Chronic Vision Loss, Persistent; Color blindness acquired/dimming; Color vision dimmimg, monocular; Decreasing visual acuity; Difficulty Focusing Eyes; Dimming vision/acute; Diplopia Double vision; Double Image Vision Confirmed; Eye pain on eye movement; Eye symptoms/signs; Eyelid Retraction; Flashing Spots/Lights in Vision; Fleeting Blindness; Iridoplegia/spared accomodation reflex; Loss vision one eye, sudden; Marcus-Gunn pupil reaction/consensory sign; Movement phosphenes/flashes/scotomata/on eye motion; Opsoclonus/chaotic eye movements; Painless Vision Loss; Pallor/white optic disk; Positive scotomata/flashes; Ptosis, unilateral (blepharoptosis); Squint/sign; Temporary blindness; Transient Blindness One Eye; Unequal pupils; Upward gaze paralysis/voluntary; Visual Problems; Visual symptoms; Sound distortion; Sudden deafness; True Vertigo Sign Confirmed; Unilateral sudden deafness; Vertigo in Elderly
Clinical Presentation & Variations: Presentation/Ataxia in a Child Acute; Presentation/Movement Disorder Ataxia Dementia Progressive; Presentation/Back pain Hyperreflexia Incontinence
Disease Progression: Course/Attacks Episodic Spells; Course/Chronic disorder; Course/Chronic only; Course/Episodic clusters of attacks; Course/Exacerbation/remission; Course/Relapsing; Course/Some residual effects/possible

Demographics & Risk Factors
Travel, Geographic & Climate Related Factors: Residence/travel/Northern Latitudes USA; Residence/travel/Temperate zone
Ethnic or Racial Factors: European racial stock/population
Established Disease Population: Patient/Multiple sclerosis; Patient/Postpartum status
Population Group: Woman; Young Adult
Occupational Factors: Occupation/Health care worker; Occupation/Nurse
Family History: Family history/Multiple sclerosis
Sex & Age Groups: Population/Adult Aged Only; Population/Adult/all; Population/Female; Population/Thirties adult; Population/Woman patient; Population/Young adult

Laboratory Tests
Abnormal Lab Findings (Non Measured): CSF abnormal; CSF Colloidal gold curve abnormal; CSF Immunoelectrophoresis abnormal; CSF Protein increased/cells absent; HLA B27 (Lab); HLA B7 (Lab); HLA DR2 (Lab); HLA DRw2 (Lab); HLA DW2 (Lab)
Abnormal Lab Findings - Decreased: Complement (total CH50) level (Lab); Lactic acid/Lactate (Lab); Lipase (Lab); Lymphocytes (Lab); Phospholipids, serum (Lab); Uric acid, serum (Lab); CSF Complement
Abnormal Lab Findings - Increased: Anti-Smooth muscle (actin) antibodies (Lab); ANA/Antinuclear antibody/Fluorescent ANA (Lab); Anti-Nuclear Antibody (ANA); Isocitric dehydrogenase (Lab); LAP/Leucine Amino Peptidase (Lab); Pyruvate, plasma (Lab); Trypsin (Lab); CSF IGA; CSF IGG; CSF IGG index; CSF IGG synthesis rate; CSF IGM; CSF Immunoglobulin; CSF LDH; CSF Monocytes; CSF Myelin basic protein; CSF Oligoclonal banding immunoelectroelectrophoresis; CSF/Beta 2 Microglobulin

Diagnostic Test Results
Other Tests & Procedures: Lumbar puncture/abnormal; OCT/Optical Coherance Tomography Thin Retina; Visual Fields Test Abnormal; Visual fields/Central scotomata; Visual Fields/Central visual field loss; TEST/Caloric/nystagmus/challenge abnormal
Pathology: PATH/Brain abnormal; PATH/Brain corpus callosum lesion/defect; PATH/Brain Focal Degeneration/Lesion; PATH/Brain white matter multifocal lesions; PATH/Brain White matter plaque astrogliosis; PATH/Brain/Leptomeningeal Lesions; PATH/Brain/White matter/deficient myelin; PATH/Cerebral demyelination/biopsy/path; PATH/Gliosis spinal cord; PATH/Perivenular/focal demyelination/reactive gliosis
Electrodiagnosis: EEG/ABR/Auditory evoked response/potential abnormal/AEP; EEG/Evoked Potential Responses Abnormal; EEG/Somatic sensory evoked response/SSEP/SSER abnormal; EEG/Visual evoked response/abnormality; Electronystagmography Abnormal; TEST/Auditory brainstem response/abnormal/ABS response
CT Scan: CT Scan/Head Brain/Corpus callosum hypoplasia/agenesis; MRI/Head Brain Abnormal; MRI/Head corpus callosum/underside lesion; MRI/Head Deep white matter/multiple lesions; MRI/Head Demyelination white matter; MRI/Head multifocal low density lesions/white matter; MRI/Head Ovoid demyelination lesions; MRI/Head periventricular white matter lesions; MRI/Head Posterior fossa white matter lesions; MRI/Head Scan Abnormal; MRI/Head T2 and fluid -attenuated inversion recovery; MRI/Head White matter lesions 6mm/larger
X-RAY With contrast: UGI/Esophagus motility disorder; UGI/Hypopharynx/pooled barium vallecula

Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs: Amyotrophic lateral sclerosis; Anxiety disorder/panic attacks; Arnold-Chiari syndrome; Brain tumor; Chronic fatique syndrome (adult 'mono'); Eaton-Lambert syndrome; Encephalitis; Encephalitis, viral; Fibromyositis/fibromyalgia syndrome; Hypochondriasis; Inflammatory polyneuropathy/demyelinating/chronic; Meniere's disease; Meningitis, chronic; Myasthenia gravis; Primary Brain Neoplasm; Stiff-man syndrome; Syringomyelia
Associated Disease & Complications - Causes: Acute respiratory failure/Respiratory arrest; Anal Incontinence; Bells palsy/Facial nerve paralysis; Bladder, neurogenic uninhibited; Blindness, central; Brain stem lesion; Brown-Sequard syndrome; Cerebral sensory cortex lesion; CNS disease/involvement; Color blind; Constipation; Corpus callosum defect/agenesis; Deafness; Deafness, sensorineural; Dementia; Depression; Esophageal motility disorder; Esotropia; Extrapyramidal disease/manifestation; Facial nerve palsy/secondary; Gastroparesis/atony; Hemiparesis; Hemiplegia; Hypouricemia; Impotence/Erectile dysfunction disorder; Internuclear ophthalmoplegia syndrome; Meningitis, chronic; Multiple sclerosis; Myelitis, transverse; Myelopathy manifestations/involvement; Neurobehavior Problems; Neurogenic bladder/cord; Obstipation; Optic neuritis; Organic brain syndrome; Paraparesis; Paraplegia; Paraplegia, spastic; Pneumonia, aspiration; Pseudobulbar palsy syndrome; Psychosis; REM Behavior disorder/RBD; Spinal cord lesion/dysfunction; Transverse myelitis, subacute; Trigeminal neuralgia; Urinary bladder retention; Vocal cord paralysis; Gastropathy Atonic; Ataxia Disorder; Demyelinating Disease; Facial Paralysis; Intracranial Lesion; Acute Urinary Retention; Oculogyric Crisis; Deafness Acquired
Disease Synergy: Synergy/Environmental extremes/temperature; Synergy/Fever; Synergy/General stress; Synergy/Heat stress; Synergy/Pregnancy

Disease Mechanism & Classification
Class: CLASS/Neurologic (category); CLASS/Spinal cord disorder (ex)
Pathophysiology: Pathophysiology/Cytokine gene polymorphism; Pathophysiology/Gene locus 1q31-q32; Pathophysiology/Gene locus Chromosome 1; Pathophysiology/Gene Locus Identified/OMIM database; Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations); Pathophysiology/Multisystem disease; Pathophysiology/Delayed gastric emptying/gastrostasis; Pathophysiology/Cerebral demyelination; Pathophysiology/CNS-Systemic Vertigo; Pathophysiology/Corpus callosum defect; Pathophysiology/Demyelination; Pathophysiology/Midbrain/mesencephalon lesion; Pathophysiology/Neurologic degenerative disorder (ex); Pathophysiology/Posterior columns cord def
Process: PROCESS/Allergy/collagen/autoimmune (category); PROCESS/Autoimmune disorder (ex); PROCESS/Great imitators/diseases (ex); PROCESS/Hereditary/Genetic predisposition (ex); PROCESS/Inflammatory/Allergy/immune (ex); PROCESS/Use/Age/atrophic disorder (category); PROCESS/CNS/White matter disorder (ex); PROCESS/Myelin involvement/disorder (ex)

Synonyms
Synonym: Synonym/Disseminated sclerosis; Synonym/MS

Treatment
Drug Therapy - Contraindication: RX/Adalimumab (Humira) injection; RX/Gamma interferon (Actimmune)
Drug Therapy - Indication: RX/Beta interferon; RX/Cladribine (Leustatin); RX/Corticosteroid (Cortisone); RX/Fingolimod (Gilenya); RX/Glatiramer (Copaxone); RX/IL-12/IL-23 Antagonist (Ustekinumab/Stelara); RX/Interferon B-1a (Avonex/Rebif); RX/Interferon B-1b; RX/Mitoxantrone (Novantrone); RX/Muscle relaxant medication; RX/Natalizumab (Tysabri); RX/Teriflumonide (Aubaglo); RX/Teriflunomide (Aubagio); RX/Vitamin D; SX/Stem cell transplant potential/future
Other Treatments: TX/Physical therapy; TX/Plasma exchange/FFP; TX/Plasmapheresis/exchange.

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