Clinical
Demographics
Lab
Diagnostic
Diseases
Classification
Synonyms
Treatment

Disease Comparison Results (show all mode) For:

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Lupus erythematosis, systemic

Found: 579 | Differences: 500

Diabetes mellitus

Found: 498 | Differences: 418

Diabetes mellitus and Lupus erythematosis, systemic sharing 76 common findings. ( show all, show common, show differences)

Clinical Manifestations
- Signs & Symptoms
  - Fever Non Infection
  - Facial Malar flush/rash
  - Lupus-like butterfly rash,face
  - Plethora/Red face/Ruddy look
  - Rash/nasal area
  - Sun exposed areas/face, arms/involved
  - Acute Chest Pain in Children
  - Diastolic hypertension
  - Nailfold capillary/giant loops sign
  - Osler's nodules/finger-tips/Osler's nodes
  - Red/erythema skin discoloration
  - Annular lesions rash
  - Baldness/Alopecia
  - Bruising/Ecchymosis
  - Cheek/facial skin distribution
  - Cicatrical alopecia
  - Depigmented patches, skin
  - Discoid rash
  - Erythroderma
  - Face skin lesions
  - Facial erythema
  - Facial flushing/Beet red
  - Facial rash
  - Facial rash sparing nasolacrimal folds
  - Fever and Rash
  - Fingernails Telangiectasias
  - Hypopigmentation
  - Janeway lesions (palms/soles)
  - Koilonychia/Spoon nails
  - Leg Ulcers in Elderly
  - Mucocutaneous rash/signs
  - Nailfold infarcts
  - Non-pruritic rash
  - Non-scarring Alopecia/balding
  - Papulosquamous rash
  - Periungual redness
  - Photosensitivity/Sunsensitive skin
  - Plaques/cutaneous
  - Porcelain red-ringed atrophic spots
  - Pruritis Itching
  - Rash
  - Rash face/exposed areas/arms/neck
  - Rash hand/foot areas
  - Rash/polycyclic/multidiscoid
  - Skin lesions
  - Skin sloughing/denuded/raw/oozing areas
  - Splinter hemorrhage/nailbed
  - Subepidermal Blisters
  - White skin discoloration
  - Oral-genital ulcers
  - Penis Rash
  - Penis ulcer/lesion
  - Excessive/easy bruising tendency
  - Abdominal Pain
  - Anorexia in Children
  - Anorexia in Elderly
  - Anorexia/Decreased appetite
  - Nausea
  - Vomiting
  - Weight loss in Elderly
  - Oral erythematous lesion
  - Oral lesion/ulcer
  - Oral mucosa white lesions
  - Oral Ulcers in Children
  - Oral Ulcers in Elderly
  - Oral Vesicles
  - Painless oral ulcers
  - Parotid swelling
  - Stomatitis Blisters/blebs
  - Ulcerative stomatitis
  - Lymphadenopathy
  - Lymphadenopathy, systemic
  - Hepatomegaly
  - Hepatosplenomegaly
  - Palpable Liver
  - Muscle weakness
  - Telangiectasia Nailbeds
  - Behavior problems
  - Confusion/agitation on exam
  - Confusion/Disoriented
  - Cranial nerve abnormalities/involvement/signs
  - Glove/stocking hypesthesia
  - Headache
  - Nasal speech/regurgitation
  - Paresthesias
  - Seizures
  - Dyspnea
  - Hemoptysis
  - Pleural Friction Rub.
  - Pleuritic chest pain
  - Shortness of breath/SOB
  - Depressed/discouraged/sad
  - Psychiatric manifestations/problems/difficulties
  - Arthralgias Polyarthralgias
  - Arthritis and Heart murmur
  - Arthritis and weight loss
  - Arthritis with Abdominal Pain
  - Arthritis with Muscle Weakness
  - Arthritis with rash/dermatitis
  - Asymmetric arthritis/multiple joints
  - Asymmetric Oligoarthropathy
  - Distal interphalageal joint arthritis
  - Joint effusion
  - Joint exam/signs
  - Joint inflammation signs
  - Joint Pains
  - Joint pains Arthralgias in Children
  - Joint pains Arthralgias in Elderly
  - Joint Swelling
  - Limp
  - Limping gait/orthopedic/antalgic
  - Monoarticular Arthritis/One joint acute
  - Multiple Joint Arthritis
  - Oligoarthritis syndrome/signs
  - Polyarticular Joint Pain
  - Symmetrical arthritis (signs)
  - Nasal congestion
  - Nasal/Hyponasal sound to voice
  - Nasopharyngeal ulcerations
  - Parotid Gland Enlargement
  - Hematuria
  - Splenomegaly
  - Chronically ill patient/signs
  - Enervated/extreme acute fatigue
  - Episodic symptoms/events
  - Fatigue/chronic
  - Fatigue/tiredness/exhaustion
  - Fever
  - Fever and Normal Sed Rate
  - Fever Febrile Possible
  - Fever of unknown origin/chronic fever
  - Fever Remittant/Recurrent
  - Fever with High sed Rate
  - Fever, intermittant/recurrent
  - Flu-Like Syndrome
  - Good days/Bad days/'Blahs' feelings
  - High body temperature
  - Malaise
  - Multiple organ/system failure patient
  - Multisystem disease/signs
  - Pallor
  - Total body pain/truncal/extremities
  - Weight loss
  - Bloodshot eyes/Conjunctival injection
  - Eye Pains, Bilateral
  - Lacrimal gland enlarged
  - Periorbital/ocular rash
  - Red Eyes Bilateral
  - Scleral Injection
  - Visual symptoms
- Typical Clinical Presentation
  - Arthritis with Subcutaneous/Skin Nodules
  - Males sicker than females/characteristic
- Clinical Presentation & Variations
  - Presentation/Hypertension Abrupt Onset
  - Presentation/Recurrent Pericarditis
  - Presentation/ Papular Rash Face Upper Arms
  - Presentation/Recurrent Aseptic Meningitis
  - Presentation/Pleural Effusions Recurrent
  - Presentation/Pancreatitis Kids Recurrent
  - presentation/Acute polyarthritis syndrome Days
  - Presentation/Arthritis Fever Rash
  - Presentation/Arthritis Syndrome with Eye Lesions
  - Presentation/Fever Arthritis signs
  - Presentation/Single Joint Arthritis
  - Nephritis Syndrome Low Complement
  - Presentation/Glomerulonephritis Rapid Progressive
- Disease Progression
  - Course/Chronic disorder
  - Course/Chronic only
  - Pancytopenia with Normal Marrow
Demographics & Risk Factors
- Ethnic or Racial Factors
  - American Indian population
  - Asian population
  - Black/African american population
  - Hispanic/Latino population
- Recent Event
  - Recent/Sunburn/severe
- Established Disease Population
  - Patient/Antiphospholipid/anticardiolipin disease
  - Patient/Autoimmune disorder
  - Patient/Collagen disease
  - Patient/Isoniazid (INH/Nydrazid) treatment
  - Patient/Lupus erythematosis, systemic
  - Patient/Scleroderma
  - Patient/Chronic lymphocytic leukemia
  - Patient/Hodgkins disease
  - Patient/Rheumatoid arthritis
- Population Group
  - Middle Age Adult
  - Population/Immigrant population
  - Woman
  - Young Adult
  - Young Asian Women Population
- Occupational Factors
  - Occupation/Health care worker
  - Occupation/Nurse
- Family History
  - Family history/Arthritis
- Sex & Age Groups
  - Population/Adult ('twenties')
  - Population/Adult/all
  - Population/Female
  - Population/Middle-aged adult
  - Population/Woman patient
  - Population/Young adult
Laboratory Tests
- Microbiology & Serology Findings
  - Serum specific antibodies increased
- Abnormal Lab Findings (Non Measured)
  - PLEURAL Exudate
  - Acute inflammatory markers elevated (Lab)
  - Anaphylatoxin C3a/des Arg present (Lab)
  - Bleeding time prolonged/platelet count normal (Lab)
  - Chronic lymphopenia
  - Left shifted differential smear (Lab)
  - Leukopenia
  - Low WBC/Left shift/Low platelets (Lab)
  - Lupus anticoagulant/level/present (Lab)
  - Lymphopenia
  - Normocytic Anemia/High Retic count
  - Normocytic anemia/low retic count
  - PFA100 (Platelet Function Assay/?) abnormal
  - PTT increased normal PT (Lab)
  - URINE Dipstick /Blood abnormal
  - URINE Sediment/Urinalysis abnormal
  - Class II HLA (Lab)
  - HLA B8 (Lab)
  - HLA DR2 (Lab)
  - HLA DR3 (Lab)
  - HLA DR4 (Lab)
  - HLA DRw3 (Lab)
  - HLA Specific association (Lab)
- Abnormal Lab Findings - Decreased
  - Antithrombin III (Lab)
  - WBC
  - Albumin, serum (Lab)
  - C1-esterase inhibitor titer (Lab)
  - C3, serum (Lab)
  - Complement (total CH50) level (Lab)
  - Haptoglobin, serum (Lab)
  - Hematocrit (Lab)
  - Hemoglobin (Lab)
  - Leukocyte Alkaline phosphatase (Lab)
  - Lymphocytes (Lab)
  - Neutrophiles (Lab)
  - Platelet count (Lab)
  - Platelet survival (Lab)
  - RBC/Red Blood Count (Lab)
  - Transferrin saturation (Lab)
  - WBC/White Blood Cell Count/Leukocytes (Lab)
  - CSF Complement
  - SYNOVIAL C3(Complement)
  - SYNOVIAL C4(Complement)
  - SYNOVIAL Complement
  - SYNOVIAL Glucose
  - PLEURAL Glucose
- Abnormal Lab Findings - Increased
  - Anti-B2-glycoprotein I (Lab)
  - Anti-cardiolipin (Lab)
  - Anti-Cytoplasmic ribosomes antibodies (Lab)
  - Anti-DNA antibody (double stranded) (Lab)
  - Anti-DNA-Histone (DNP) antibodies (Lab)
  - Anti-Histone antibody (Lab)
  - Anti-mitochondrial antibodies/AMA (Lab)
  - Anti-neutrophilic/cytoplasm antibody (ANCA) (Lab)
  - Anti-PCNA antibody (Lab)
  - Antiphospholipid antibodies (Lab)
  - Anti-Ribosomal protein S10 (Lab)
  - Anti-RNA antibody/Nrnp (Lab)
  - Anti-RNA/ENA Sm (Smith) antibody (Lab)
  - Anti-RNP (U1RNP) antibody (Lab)
  - Anti-Roux in La (nucleotides) (Lab)
  - Anti-SCL-70 (antinucleotide) (Lab)
  - Anti-SSB (La) antibodies/Cytoplasm antigen (Lab)
  - Anti-ssDNA (single stranded) antibody (Lab)
  - Febrile Agglutinins (Lab)
  - Acute lymphopenia/transient
  - Alpha-1-antitrypsin globulin level (Lab)
  - Amylase, serum (Lab)
  - ANA, homogenous/serum (Lab)
  - ANA, peripheral/serum (Lab)
  - ANA, speckled (Lab)
  - ANA/Antinuclear antibody/Fluorescent ANA (Lab)
  - Anti-DNA Antibody
  - Anti-ENA (Extractable Nuclear Antigen) Level
  - Anti-Nuclear Antibody (ANA)
  - Anti-Nucleosome Chromatin Antibodies (Lab)
  - Anti-Sjogren ANA (Ro/La/SS-C)
  - Anti-SSA (Ro) Antibody
  - Biologic false positive (serology) (Lab)
  - Bleeding time, Duke (Lab)
  - BUN/Blood urea nitrogen (Lab)
  - Cold agglutinins, serum (Lab)
  - Creatine, serum (Lab)
  - Cryoglobulins (Lab)
  - Direct Coombs test (Lab)
  - Eosinophiles (Lab)
  - Ferritin, serum (Lab)
  - Fibrin Split Products/FSP/Dimers/Monomers (Lab)
  - Fibrinogen, plasma (Lab)
  - Gamma globulin (Lab)
  - Globulin, serum (Lab)
  - Glycoproteins (Lab)
  - IGA/Immunoglobulin A (Lab)
  - IGD/Immunoglobulin D (Lab)
  - IGG/Immunoglobulin G (Lab)
  - IGM/Immunoglobulin M (Lab)
  - LDH isoenzyme 4 (Lab)
  - LDH/Lactic Dehydrogenase (Lab)
  - LE Prep/Lupus erythematosis cell prep (Lab)
  - Monocytes (Lab)
  - Monocytosis
  - P-ANCA antibodies (Lab)
  - Plasma cells, blood (Lab)
  - Potassium, serum (Lab)
  - PTT/Partial Thromboplastin Time/Activated PTT (Lab)
  - Rheumatoid factor (Lab)
  - Scleroderma Antibodies (SCL-70)
  - Sed Rate/ESR/Sedimentation rate (Lab)
  - Serologic syphilis test/STS/VDRL/Hinton (Lab)
  - Sjogren ANA Antibodies (Ro/La/SS-C)
  - Thromboplastin generation time (Lab)
  - Viscosity, serum (Lab)
  - Vitamin B12 binding capacity (Lab)
  - URINE Casts erythrocytes
  - URINE Casts/Protein casts
  - URINE Creatine
  - URINE Lactic dehydrogenase
  - URINE Monocytes
  - URINE Mucopolysaccharides
  - URINE Myoglobin
  - URINE Protein (albumin)
  - URINE Red blood cells
  - CSF Protein
  - SYNOVIAL Antinuclear antibodies
  - SYNOVIAL Lymphocytes
  - PLEURAL Adenosine Deaminase/ADA
  - PLEURAL Antinuclear antibodies
  - PLEURAL Eosinophiles
Diagnostic Test Results
- Other Tests & Procedures
  - Skin test anergy
  - Athrocentesis/Joint tap/Abnormality
- Pathology
  - PATH/Arteritis/immune complex deposition
  - PATH/Periarterial sclerosis/Tissue specimen
  - BX/Skin biopsy/Cutaneous vasculitis/leukoclastic
  - BX/Skin biopsy/Leukoclastic vasculitis
  - BX/Renal glomerulous cellular infiltrate
  - PATH/Cellular necrosis/pathology tissue specimen
  - PATH/Collagen swelling/tissue specimen
  - PATH/Fibrinoid degeneration/tissue
  - PATH/Granulomatous tissue/specimen
- X-RAY
  - Xray/Chest abnormal
  - Xray/Subcutaneous ossification centers/calcification
  - Xray/Calcification in fingertips
  - Xray/Muscle calcification
  - Xray/Soft tissue calcification/muscle/subcutaneous
  - Xray/Bilateral basilar infiltrate/Chest
  - Xray/Chest/Lung fields/Abnormal
  - Xray/Pleural fluid/Chest
  - Xray/Odontoid erosion/Neck
  - Xray/Periarticular knee calcifications
  - Xray/Ribs inferior bone resorption
  - Xray/Ribs, notching margins
Associated Diseases & Rule outs
- Associated Disease & Complications - Rule Outs
  - Acne rosacea
  - Adult Still's disease/RA presentation
  - Ascariasis, pulmonary larval infestation
  - Bronchiolitis obliterans
  - Collagenosis, unclassified
  - Fibromyositis/fibromyalgia syndrome
  - Glomerulonephritis, acute
  - Goodpasture's syndrome
  - Juvenile rheumatoid arthritis/chronic
  - Lupus, discoid, chronic
  - Mixed connective tissue disease (MCTD)
  - Paroxysmal cold hemoglobinuria
  - Pemphigoid, bullous
  - Pemphigus
  - Polyarteritis nodosa
  - Preeclampsia of pregnancy
  - Psoriasis
  - Rheumatic fever
  - Rheumatoid arthritis
  - Scleroderma, progressive systemic
  - Tinea corporis
- Associated Disease & Complications - Causes
  - Abortion, habitual (spontaneous,recurrent)
  - Abortion/miscarriage
  - Acute Renal Failure
  - Acute Tubulointerstitial Nephropathy
  - Alopecia areata
  - Alopecia totalis/universalis
  - Amyloidosis, secondary
  - Amyloidosis, systemic
  - Anemia
  - Anemia of chronic disease
  - Anemia, aplastic
  - Anergic status
  - Anticardiolipin syndrome
  - Aortic regurgitation
  - Aphthous stomatitis Aphthous oral lesions
  - Arthritis
  - Aspergillosis, invasive pulmonary type
  - AV node lesion/infiltrate
  - Avascular necrosis bone/process
  - Azotemia in Elderly
  - Azotemia/Acute
  - Bone Marrow Fibrosis
  - Bullous Stomatitis
  - Cardiomyopathy
  - Cardiomyopathy, secondary
  - Cellular immunity defect/deficiency
  - Cerebral Angiitis syndrome
  - Cerebral thrombosis
  - Cerebral vascular accident
  - Chronic hives/urticaria
  - Circulating anticoagulants disorder (Lab)
  - Circulating coagulation inhibitor status
  - CNS disease/involvement
  - Collagen disease
  - Collagen vascular disease
  - Constrictive pericarditis/chronic
  - Convulsions (grand mal)
  - Cryptococcal meningitis
  - Cryptococcosis, disseminated
  - Cutaneous vasculitis
  - CVA Hematologic disorders/Cause
  - CVA Inflammatory disorders/cause
  - Dacryoadenitis, acute
  - Dementia
  - Depression
  - Depression, reactive
  - Dermatitis/Chronic rash
  - Dermatomyositis
  - Disseminated intravascular coagulation
  - Eclampsia of pregnancy
  - Encephalopathy/CNS effect
  - Eosinophilia Hypereosinophilia
  - Erythema multiforme
  - Esophageal candidiasis
  - Esophageal motility disorder
  - Facial nerve palsy/secondary
  - Glomerulonephritis, acute
  - Glomerulonephritis, membranous
  - Glomerulonephritis, rapidly progressive
  - Glomerulonephritis/Glomerulitis
  - Guillain-Barre syndrome
  - Hallucinations
  - Hemolysis anemia/acute/active
  - Hemolytic Anemia
  - Hemolytic anemia/autoimmune
  - Hemolytic-uremic syndrome
  - Hyperamylasemia
  - Hyperglobulinemia
  - Hyperkalemia
  - Hypersplenism
  - Hypertension
  - Hypocomplementemia
  - Hypogammaglobulinemia
  - Hypogammaglobulinemia, acquired
  - Inappropriate ADH secretion syndrome
  - Inflammatory myopathy
  - Interstitial lung involvement/manifestation
  - Intestinal/gut lymphoma
  - Iritis
  - Leukocytoclastic angiitis
  - Livedo reticularis
  - Lupus cerebritis
  - Lupus erythematosis, systemic
  - Lupus nephritis
  - Lupus, discoid, chronic
  - Lymphocytopenia
  - Microangiopathic anemia/disease
  - Mitral regurgitation
  - Mononeuritis, multiplex
  - Multi-radicular Polyneuropathy syndrome
  - Myasthenia gravis
  - Myelitis, transverse
  - Myelofibrosis
  - Myelofibrosis secondary
  - Myelopathy manifestations/involvement
  - Myocarditis
  - Nasal septum perforation
  - Neonatal thrombocytopenia
  - Nephritis, interstitial
  - Nephritis, non-allergic interstitial
  - Nephrosis/secondary disease
  - Nocardia, pulmonary
  - Organic brain syndrome
  - Pancreatitis, acute
  - Pancytopenia
  - Pericardial effusion
  - Pericarditis, acute
  - Peripheral neuropathy
  - Peritonitis. acute
  - Peritonitis/aseptic
  - Photodermatosis
  - Photosensitivity dermatitis
  - Phototoxicity
  - Platelet manifestation/defect
  - Pleural Effusion
  - Pleurisy
  - Pleurisy with effusion
  - Pleuropericarditis
  - Pneumococcus infection
  - Pneumocystis Jiroveci/Carinii Pneumonia (PCP)
  - Pneumonia, lymphoid interstitial
  - Pneumonia, pneumococcal
  - Pneumonia/Bronchopneumonia
  - Polyarteritis nodosa
  - Polyarthritis in Children
  - Polyarthritis syndrome/Multiple joints/weeks
  - Polyneuritis
  - Protein losing enteropathy
  - Proteinuria
  - Pseudopilade of Brocq
  - Pseudotumor cerebri
  - Psychosis
  - Pulmonary Interstitial fibrosis, secondary
  - Raynaud's disease
  - Raynaud's syndrome
  - Renal tubular acidosis, distal
  - Renal tubule acidosis, acquired
  - Renal vasculitis
  - Retinal hemorrhage
  - Retroperitoneal hemorrhage
  - Scarring alopecia
  - Scleritis/Episcleritis
  - Serositis
  - Sjogren's sicca syndrome
  - Stomatitis
  - Tamponade, cardiac/pericardial
  - Telangiectasia
  - Tendonopathy
  - Thrombocytopenia
  - Thrombocytopenia in Children
  - Toxoplasmosis, disseminated
  - Transient ischemic attack/cerebral
  - Transverse myelitis, subacute
  - Urticaria/hives
  - Vitiligo
  - Hypersensitivity/Leukoclastic Vasculitis
  - Anemia in Elderly
  - Polyneuropathy
  - Recurrent Meningitis
  - Monoarthritis Acute
  - PolyArthritis
  - Proteinuria in Children
  - Proteinuria in Elderly
- Disease Synergy
  - Synergy/General stress
  - Synergy/Immunizations/vaccinations
  - Synergy/On medications/medication
  - Synergy/Sunlight exposure
Disease Mechanism & Classification
- Class
  - CLASS/Vascular Small Vessel Disorder
  - CLASS/Multisystem/organ involvement/pathology (ex)
  - CLASS/Systemic/no comment (category)
- Pathophysiology
  - Pathophysiology/Circulating immune complex
  - Pathophysiology/Cytokine gene polymorphism
  - Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
  - Pathophysiology/Multisystem disease
  - Pathophysiology/Urticaria/Circulating immune complex
  - Pathophysiology/Hypersensitivity Vasculitis
  - Pathophysiology/Leukoclastic Vasculitis
  - Pathophysiology/Small Vessel Vasculitis
  - Pathophysiology/Hemolytic process/effect
  - Pathophysiology/Hypercoaguability
  - Pathophysiology/Mechanical Hemolysis
  - Pathophysiology/CD4/T-cell synovitis
  - Pathophysiology/Nephritis/tubulointerstitial
  - Pathophysiology/Renal manifestations/involvement
  - Pathophysiology/Anti-Chromosomal DNA antibodies
  - Pathophysiology/Apoptosis/cell death deregulation/genetic
  - Pathophysiology/Chemotaxis failure/phagocytes/effect
  - Pathophysiology/Immune physiology/defective
  - Pathophysiology/Mucin/small duct (mucus glands) def
  - Pathophysiology/Ischemic optic neuritis
- Process
  - PROCESS/Allergy/collagen/autoimmune (category)
  - PROCESS/Collagen disease (ex)
  - PROCESS/Ethnic predilection (ex)
  - PROCESS/Great imitators/diseases (ex)
  - PROCESS/Hereditary/Genetic predisposition (ex)
  - PROCESS/Inflammatory/Granulomatous disease (ex)
  - PROCESS/Photodermatosis (ex)
  - PROCESS/Glomerular lesions/disorder (ex)
  - PROCESS/Granulomatous Disease
  - PROCESS/Systemic illness (ex)
Synonyms
- Synonym
  - Synonym/SLE
Treatment
- Drug Therapy - Contraindication
  - RX/Gamma interferon (Actimmune)
  - RX/Procainamide (Pronestyl)
- Drug Therapy - Indication
  - RX/Azathioprine (Imuran)
  - RX/Hydroxychloraquin (Plaquenil)
  - RX/Immune-suppression
  - RX/Prednisone (Deltasone)
  - SX/Stem cell transplant potential/future
- Other Treatments
  - TX/Avoid sunlight exposure
  - TX/Platelet transfusion

Clinical Manifestations
- Signs & Symptoms
  - Decreased peripheral pulses
  - Carbuncle/recurrent/present/sign
  - Delayed/poor wound healing
  - Dry skin/scaling dry skin
  - Foot Lesion Ulcerating
  - Furuncles present
  - Intertrigo
  - Leukonychia/white nails
  - Paronychium/swelling nail/finger
  - Pruritis Itching
  - Recurrent paronychium/sign
  - Semilunar nail zone large/Terry nails
  - Terry's Nails/Whitening
  - Yellow skin discoloration
  - Delayed adolescence/secondary sex changes
  - Delayed female adolescence
  - Delayed male adolescence/pubescence
  - Delayed Puberty
  - Excess Thirst in Children
  - Excess Thirst in Elderly
  - Large baby/birth weight increased
  - Impotence, relative
  - Abdominal Pain
  - Appetite increased
  - Chronic Diarrhea in a Child
  - Constipation in Children
  - Diarrhea
  - Diarrhea in Children
  - Diarrhea, chronic
  - Diarrhea, nocturnal/movement in night
  - Excessive thirst/polydipsia
  - Failure to Thrive
  - Failure to Thrive Child
  - Failure to thrive/infant sign
  - Increased abdominal girth/Potbelly
  - Polyphagia
  - Rectal pruritis
  - Sweet tooth appetite
  - Vomiting
  - Vomiting in Children
  - Weight loss good appetite
  - Weight loss in Children
  - Weight loss in Elderly
  - Dry mouth/Mucous membranes
  - Parotid swelling
  - Salivary Gland Enlargement
  - Hepatomegaly
  - Palpable Liver
  - Yellow skin/white sclera
  - Weak/Weak as a kitten (symptom)
  - Absent knee reflexes
  - Anesthetic hypoesthetic limbs/areas
  - Argyl-Robertson pupil
  - Burning feet
  - Cranial nerve abnormalities/involvement/signs
  - Glove/stocking hypesthesia
  - Hyporeflexia/DTRs decreased
  - Motor and sensory neuropathy/Polyneuropathy signs
  - Paresthesias
  - Weakness/Diffuse motor loss
  - Cheesy/whitish vaginal discharge
  - Vulva itching
  - Palmar chieropathy/prayer sign
  - Tall child
  - Anosmia/Loss of sense of smell
  - Decreased sense of smell
  - Parotid Gland Enlargement
  - Diuresis/Large urine volumes
  - Nocturia
  - Nocturia in Children
  - Nocturia in Elderly
  - Nocturnal polyuria/polydipsia
  - Polyuria
  - Polyuria and polydipsia
  - Urinary incontinence in Children
  - Urine Frequency
  - Chronically ill patient/signs
  - Endomorph habitus
  - Enervated/extreme acute fatigue
  - Episodic symptoms/events
  - Fatigue/chronic
  - Fatigue/Tiredness in Elderly
  - Fatigue/tiredness/exhaustion
  - Nocturnal water drinking
  - Spells/Episodes of weakness
  - Truncal obesity
  - Water drinking increased
  - Weakness
  - Weakness non-neuromuscular/systemic
  - Weight gain
  - Weight loss
  - Blurred vision
  - Cornea Insensitive
  - Decreasing visual acuity
  - Dimming vision/acute
  - Diplopia/Double vision
  - Eye symptoms/signs
  - Iridoplegia/spared accomodation reflex
  - Night blindness/Impaired night vision
  - Retinal exudates
  - Retinopathy signs on exam
  - Visual acuity decreasing
  - Xanthalasma
  - Calcification/pinna cartilage/sign
- Clinical Presentation & Variations
  - Presentation/Progressive Motor Sensory Polyneuropathy
  - Presentation/Recurrent pneumonia Child
- Disease Progression
  - Course/Chronic disorder
  - Course/Chronic only
  - Course/Life-span decreased
Demographics & Risk Factors
- Ethnic or Racial Factors
  - American Indian population
- Past History
  - Past history/Aortic surgery/remote
  - Past history/Stein-Leventhal/polycystic ovaries
- Established Disease Population
  - Patient/Cystic fibrosis
  - Patient/Gout
  - Patient/Hemochromatosis
  - Patient/Obesity/massive
  - Patient/Arteriosclerosis
  - Patient/Arteriosclerosis/lower extremities
  - Patient/Arteriosclerotic heart disease
  - Patient/Acromegaly
  - Patient/Hashimoto's thyroiditis
  - Patient/Diabetic/autonomic disorder
  - Patient/Diabetes mellitus
  - Patient/Type I/diabetic (juvenile)
  - Patient/Renal artery stenosis
- Population Group
  - Aged Adult
  - Child
  - Population/Pediatrics population
- Family History
  - Family history/Diabetes mellitus
- Sex & Age Groups
  - Population/Adult Aged Only
  - Population/Adult/all
  - Population/Child
  - Population/Children/all
  - Population/Elderly Aged
  - Population/Seventies Adult
  - Population/Sixties-adult
Laboratory Tests
- Abnormal Lab Findings (Non Measured)
  - Ketonuria (Lab)
  - Lactescent/lipemic serum (Lab)
  - Lymphopenia
  - Serum lipids increased (Lab)
  - Specific Single Nucleotide Polymorphism/SNIP genome type
  - Class II HLA (Lab)
  - HLA B15 antigen (Lab)
  - HLA B8 (Lab)
  - HLA DR3 (Lab)
  - HLA DR4 (Lab)
  - HLA DRw3 (Lab)
  - HLA Specific association (Lab)
- Abnormal Lab Findings - Decreased
  - ApoA-I lipoprotein Level (Lab)
  - 25-OH Cholecalciferol/25-OH Vit D/Vit D3 level (Lab)
  - Aldosterone, serum (Lab)
  - HDL (High density lipoprotein) (Lab)
  - Insulin level (Lab)
  - Lymphocytes (Lab)
  - Magnesium (Lab)
  - Norepinephrine, plasma (Lab)
  - Potassium, serum (Lab)
  - Sodium, serum (Lab)
  - URINE 17-Hydroxycorticosteroids
- Abnormal Lab Findings - Increased
  - Anti-GAD antibodies
  - Anti-Glutamic Acid decarboxylase antibodies/GAD
  - Anti-Pancreatic islet cell antibodies
  - ACE/Angiotensin converting enzyme level (Lab)
  - Acute lymphopenia/transient
  - Alanine, serum (Lab)
  - Amino acids serum (Lab)
  - Basophiles (Lab)
  - Carotene/Vitamin A level (Lab)
  - Cholesterol (Lab)
  - Factor 8 (Lab)
  - Fibrinogen, plasma (Lab)
  - Fructosamine (Lab)
  - Gammaglutamyl transferase/GGT (Lab)
  - Globulin, serum (Lab)
  - Glucose, blood (Lab)
  - Glycohemoglobin (hemoglobin A1C/Glycated HGB) (Lab)
  - Growth hormone/STH, plasma (Lab)
  - Hexosaminidase (Lab)
  - Insulin level (Lab)
  - Insulin-like growth factor 1/IGF1
  - Ketones, plasma (Lab)
  - Lactic acid/Lactate (Lab)
  - Magnesium (Lab)
  - Osmolality, serum (Lab)
  - Phospholipids, serum (Lab)
  - Phosphorus, inorganic, serum (Lab)
  - Plasma Retinol
  - Plasma Retinol Binding Protein
  - Platelet count (Lab)
  - Potassium, serum (Lab)
  - Proinsulin
  - Pseudocholinesterase, serum (Lab)
  - Pyruvate, plasma (Lab)
  - Total Protein, serum (Lab)
  - Triglycerides (Lab)
  - Trypsin (Lab)
  - Uric acid, serum (Lab)
  - URINE Acetone/Ketones/Ketone bodies
  - URINE Amino acids
  - URINE Amylase
  - URINE Chloride
  - URINE Creatine
  - URINE Glucose
  - URINE Growth hormone
  - URINE Lysozyme
  - URINE Magnesium
  - URINE Potassium
  - URINE Protein (albumin)
  - CSF Glucose
  - CSF Protein
  - SYNOVIAL Glucose
Diagnostic Test Results
- Other Tests & Procedures
  - Skin test anergy
  - TEST/Glucose intolerance/GTT abnormal
- Pathology
  - BX/Liver biopsy/Fatty change in liver tissue
  - PATH/Large fatty liver
- CT Scan
  - CT/Dexa-Scan Bone density Abnormal
- X-RAY
  - Xray/Calcified artery/veins finding
  - Xray/Chest abnormal
  - Xray/Calcification in scrotum
  - Xray/Calcification seminal vesicle
  - Xray/Calcification vas deferens
  - Xray/Calcified bursa/tendon
  - Xray/Chest/Lung fields/Abnormal
  - Xray/Bone infarct
  - Xray/Periarticular knee calcifications
  - Xray/Pelvic calcification/KUB
  - Xray/Calcification ear cartilage/Skull
- X-RAY With contrast
  - SBS/Delay/Slow intestinal transit
  - UGI/Gastric retention
  - UGI/Stomach dilated atonic
  - IVP/Papillary destruction/amputation
Associated Diseases & Rule outs
- Associated Disease & Complications - Rule Outs
  - Hyperthyroidism (Graves disease)
- Associated Disease & Complications - Causes
  - Abdominal actinomycosis
  - Abdominal aortic aneurysm
  - Abortion, habitual (spontaneous,recurrent)
  - Abortion/miscarriage
  - Abscess, alveolar
  - Abscess, perianal/pararectal
  - Abscess, periapical
  - Abscess, perinephric
  - Acanthosis nigricans
  - Actinomycosis, thoracic
  - Acute anuria/renal failure
  - Adenocarcinoma, pancreas
  - Anergic status
  - Angina, unstable/crescendo/intermediate syndrome
  - Anogenital pruritis syndrome
  - Aortic occlusion distal, chronic
  - Arteriosclerosis
  - Arteriosclerosis, lower extremities
  - Arteriosclerotic heart disease
  - Arthritis Pyogenic Septic
  - Aspergillosis, invasive pulmonary type
  - Autonomic neuropathy
  - Avascular necrosis bone/process
  - Azotemia in Elderly
  - Azotemia/Acute
  - Bacteremia Septicemia
  - Bacteria intestinal overgrowth syndrome
  - Balanoposthitis
  - Blind-loop syndrome
  - Blindness
  - Blindness in Elderly
  - Breast abscess
  - Bullous Diabeticorum lesions
  - Candidiasis, cutaneous
  - Carbuncle
  - Cardiomyopathy
  - Cardiomyopathy, restrictive
  - Carotenemia
  - Carpal tunnel syndrome
  - Cataract
  - Cellulitis
  - Cellulitis, leg/ankles
  - Cellulitis, orbital
  - Cerebral embolism
  - Cerebral lacunar infarct
  - Cerebral thrombosis
  - Cerebral vascular accident
  - Cervicofacial actinomycosis
  - Chalazion
  - Charcot neuroarthropathic joint
  - Cholecystitis without gallstones
  - Cholecystitis, acute
  - Cholelithiasis
  - Chylomicronemia syndrome
  - Cleft lip/deformity
  - Cleft palate/deformity
  - Cranial nerve palsy
  - Cryptococcal meningitis
  - Cryptococcosis, disseminated
  - Cryptococcosis, pulmonary
  - Cutaneous abscess/subcutaneous
  - Dehydration
  - Diabetes mellitus
  - Diabetic amyotrophy syndrome
  - Diabetic diarrhea syndrome
  - Diabetic ketoacidosis/coma
  - Diabetic nephropathy
  - Diabetic renal dis/KW Nephropathy
  - Dupuytrens contracture
  - Eclampsia of pregnancy
  - Ejaculation, retardation
  - Embolism, atheromatous
  - Endocarditis, right heart
  - Eneuresis Bed Wetting
  - Esophageal candidiasis
  - Esophageal motility disorder
  - Fatty liver
  - Femoral neuropathy
  - Furunculosis
  - Gallbladder empyema
  - Gas gangrene
  - Gastroparesis/atony
  - Glans/foreskin moniliasis
  - Glaucoma
  - Glaucoma, open angle
  - Glomerulonephritis, membranous
  - Gram negative septicemia
  - Granuloma annulare
  - Heat stroke
  - Herpes zoster
  - Hypercholesterolemia
  - Hyperglobulinemia
  - Hyperglycemia
  - Hyperkalemia
  - Hyperlipidemia
  - Hypermagnesemia
  - Hyperosmolar coma/hyperglycemic nonketotic
  - Hypertriglyceridemia
  - Hyperuricemia
  - Hypoglycemia, functional
  - Hypokalemia
  - Hypomagnesemia
  - Hyponatremia
  - Hypouricemia
  - Impetigo/Pyoderm
  - Impotence/Erectile dysfunction disorder
  - Intestinal tuberculosis/enterocolitis/ileocecal
  - Intestine, psuedo-obstruction
  - KW/Kimmelstiel-Wilson nephropathy
  - Legionaires disease
  - Listeria meningitis
  - Liver abscess
  - Liver cell adenoma
  - Lung abscess
  - Lymphocytopenia
  - Male osteoporosis syndrome
  - Meningitis Bacterial
  - Meningitis, staphylococcal
  - Meningitis, tuberculosis
  - Meralgia paresthetica
  - Metastatic staphylococcus abscess syndrome
  - Monilia pharyngitis/Oral thrush/candida
  - Moniliasis/vaginal candidiasis
  - Mononeuritis, multiplex
  - Mucormycosis, rhinocerebral (Phycomycosis)
  - Multi-radicular Polyneuropathy syndrome
  - Myocardial infarction, acute
  - Nephrosis/secondary disease
  - Neurogenic bladder/cord
  - Obesity
  - Obesity in Elderly
  - Onycholysis
  - Osteoarthritis, degenerative
  - Osteomyelitis
  - Osteoporosis/osteopenia
  - Painful neuropathy
  - Palsy, third nerve
  - Paronychia
  - Pathologic fractures
  - Pelvic actinomycosis
  - Perianal candidiasis
  - Peripheral neuropathy
  - Peripheral vascular disease
  - Pituitary ischemic necrosis
  - Placenta Abruptio
  - Pleurisy, tuberculous
  - Pneumonia
  - Pneumonia, bacterial
  - Pneumonia, Klebsiella
  - Pneumonia, pneumococcal
  - Pneumonia, staphylococcus
  - Pneumonia/Bronchopneumonia
  - Polyhydramnios/Hydramnios
  - Polyneuritis
  - Preeclampsia of pregnancy
  - Proliferative retinopathy
  - Pruritis vulvae
  - Pseudogout (CPPD) arthritis
  - Pseudotabes syndrome
  - Puerperal infection
  - Pulmonary atypical mycobacteria infection
  - Pulmonary candidiasis
  - Pulmonary coccidioidomycosis, chronic
  - Pyelonephritis, acute
  - Pyelonephritis, chronic
  - Radioconstrast nephrotoxicity
  - Renal artery stenosis
  - Renal papillary necrosis
  - Renal tubular acidosis/type IV
  - Renal tubule acidosis, acquired
  - Retinal vein thrombosis, central
  - Retinopathy
  - Sensory neuropathy
  - Sinusitis
  - Skin infections
  - Spinal epidural abscess
  - Sprue (gluten enteropathy)
  - Staphylococcus aureus infection
  - Steatohepatitis
  - Steatosis/Non-alcoholic steatosis hepatitis/NASH
  - Superior mesenteric artery insufficiency, acute
  - Systemic mycosis/disseminated
  - Thigh cellulitis
  - Thrombocytosis
  - Transient ischemic attack/cerebral
  - Tuberculosis
  - Tuberculosis, disseminated
  - Tuberculosis, pulmonary
  - Tuberculosis, renal
  - Tuberculous pericarditis
  - Tuberculous peritonitis
  - Type IV hyperlipidemia
  - Type V hyperlipidemia
  - Vertebral osteomyelitis
  - Vertebrobasilar artery insufficiency
  - Vulvovaginitis, Fungal
  - Xeroderma
  - Leg ulcers
  - Gastropathy Atonic
  - Mononeuropathy
  - Polyneuropathy
  - Metabolic Bone Disease
  - Proteinuria in Elderly
- Disease Synergy
  - Synergy/Carbohydrate excess/diet
  - Synergy/Obesity
  - Synergy/Pregnancy
Disease Mechanism & Classification
- Class
  - CLASS/Endocrine gland (category)
  - CLASS/Pancreas/accessory (category)
- Pathophysiology
  - Pathophysiology/Abscess tendency
  - Pathophysiology/Cytokine gene polymorphism
  - Pathophysiology/Fungal infection prone
  - Pathophysiology/Gene locus 12q24.2
  - Pathophysiology/Gene locus 1p13
  - Pathophysiology/Gene locus 6p21.3
  - Pathophysiology/Gene locus Chromosome 1
  - Pathophysiology/Gene locus chromosome 12
  - Pathophysiology/Gene locus Chromosome 20
  - Pathophysiology/Gene locus Chromosome 20q
  - Pathophysiology/Gene locus Chromosome 6
  - Pathophysiology/Gene locus Chromosome X.
  - Pathophysiology/Gene Locus Identified/OMIM database
  - Pathophysiology/Gene locus Xp11.23-q13.3
  - Pathophysiology/Gene TCF7L2
  - Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
  - Pathophysiology/Hereditary disease/Adult manifestations
  - Pathophysiology/Lipid metabolism defect
  - Pathophysiology/Hypersomatotropism
  - Pathophysiology/Delayed gastric emptying/gastrostasis
  - Pathophysiology/Intestinal motility disordered
  - Pathophysiology/Acquired Neuropathy
  - Pathophysiology/Hyperglycemia/reactive/AM/Smolgi
  - Pathophysiology/Islets of Langerhans involvement
  - Pathophysiology/Osteoporosis Secondary
  - Pathophysiology/Renal manifestations/involvement
  - Pathophysiology/Poor slow recovery/ bacteria infection
  - Pathophysiology/Change in refractive index/lens
  - Pathophysiology/Dark adaptation/vision defect
  - Pathophysiology/Ischemic optic neuritis
- Process
  - PROCESS/Autoimmune disorder (ex)
  - PROCESS/Endocrine/humoral disorders (category)
  - PROCESS/Ethnic predilection (ex)
  - PROCESS/Metabolic/storage disorder (category)
  - PROCESS/Mononeuropathy tendency (ex)
  - PROCESS/Systemic illness (ex)
Synonyms
- Synonym
  - Synonym/DM
  - Synonym/LADA (Late autoimmune Diabetes adult) variant
  - Synonym/MODY (Maturity Onset Diabetes of Young)
Treatment
- Drug Therapy - Contraindication
  - RX/Ergotamine (Ergostat)
  - RX/Glucose
- Drug Therapy - Indication
  - RX/Acarbose (Precose)
  - RX/Chlorpropamide (Diabinese)
  - RX/Exenatide (Byetta)
  - RX/Glipizide (Glucotrol)
  - RX/Glyburide (Micronase)
  - RX/Insulin
  - RX/Multivitamin supplements
  - RX/Nateglinide (Starlix)
  - RX/Oral hypoglycemic medication
  - RX/Repaglinide (Prandin)
  - RX/Rosiglitazone (Avandia)
  - RX/Tolazamide (Tolinase)
  - RX/Tolbutamide (Orinase)
- Other Treatments
  - TX/Diet restriction treatment.
  - TX/Exercise/aerobic
  - TX/Weight loss diet
  - TX/Potential Stem Cell Research RX

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