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Disease Comparison Results (show all mode) for Abetalipoproteinemia (Bassen Kornzweig) and Quinidine (Quinaglute/Cardioquin) Administration/Toxicity

Clinical
Demographics
Lab
Diagnostic
Diseases
Classification
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Treatment
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Quinidine (Quinaglute/Cardioquin) Administration/Toxicity

Found: 128 | Differences: 126

Found: 120 | Differences: 118

Abetalipoproteinemia (Bassen Kornzweig) and Quinidine (Quinaglute/Cardioquin) Administration/Toxicity sharing 2 common findings. (show all, show common, show differences)

Clinical Manifestations
Signs & Symptoms: Dizzy on Standing/Giddy Response; Hypotension with Relative Bradycardia; Low Blood Pressure; Orthostatic drop in blood pressure; Slow pulse/Bradycardia; Tachycardia/Fast heart rate; Rash; Bowel Habit Change; Diarrhea; Diarrhea, chronic; Diarrhea, explosive; Diarrhea, fulminant; Diarrhea/painless; Fasting intolerant; Nausea; Vomiting; Tinnitus; Tinnitus in Elderly
Clinical Presentation & Variations: Presentation/Shock Normal Heart Rate

Laboratory Tests
Abnormal Lab Findings (Non Measured): Fasting hypoglycemia (Lab)
Abnormal Lab Findings - Decreased: Glucose, blood (Lab); Platelet count (Lab)
Abnormal Lab Findings - Increased: Anti-cardiolipin (Lab); Anti-Histone antibody (Lab); Digoxin serum level (Lab); Direct Coombs test (Lab); PT -Prothrombin time (Lab)

Diagnostic Test Results
Isotope Scan: Isotope/RAI Uptake low/thyroid scan (I 123); Isotope/RAI uptake/quantitative high thyroid (I 123)
EKG (ECG): EKG/Prolonged PR Interval (ECG); EKG/Prolonged QRS interval (ECG); EKG/QRS greater than .12 ms/wide (ECG); EKG/Widened QRS pattern (ECG); EKG/Drug induced QT prolongation (ECG); EKG/Prolonged QT interval (ECG); EKG/ST-T changes (ECG); EKG/Flat T Waves (ECG); EKG/Persistent T Wave inversion (ECG); EKG/Prominent U Waves (ECG); EKG/T Wave inversion (ECG); EKG/T Waves/notched (ECG); EKG/T Waves/widened (ECG); EKG/AV Nodal Block/Complete; EKG/Interventricular block/non-specific (ECG); EKG/Sinus pause (ECG); EKG/Changes/abnormalities (ECG)

Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs: Digitalis toxicity/poisoning
Associated Disease & Complications - Causes: Acute gastroenteritis; Anogenital pruritis syndrome; Brady-arrhythmia; Bradyarrhythmias; Cardiac arrhythmias; Cardiac conduction defects; Cinchonism/Salicylism syndrome; Congestive heart failure; Death/Unanticipated; Digitalis toxicity/poisoning; Drug induced Arrhythmias; Drug induced Diarrhea.; Drug induced Myopathy.; Drug induced Neutropenia.; Drug induced Photosensitivity rash; Drug induced Prolonged Q-T interval; Drug induced Thrombocytopenia.; Drug rash/Drug induced rash; Granulocytopenia/Neutropenia; Heart block, complete; Hemolysis anemia/acute/active; Hemolytic anemia/autoimmune; Hypotension; Lichen planus; Livedo reticularis; Orthostatic syncope Hypotension; Photosensitivity dermatitis; Phototoxicity; Pruritis ani; Pulmonary edema; Stokes-Adams attacks; Syncope/Fainting; Thrombocytopenia, autoimmune; Torsades de pointes/ventricular tachycardia; Toxic amblyopia syndrome; Ventricular fibrillation; Ventricular tachycardia; Ventricular tachycardia/arrest; Ventricular, paroxysmal tachycardia; Lichenoid Dermatitis; Lichenoid Mucositis
Disease Synergy: Synergy/Digitalis/digoxin toxicity

Disease Mechanism & Classification
Drugs: DRUG/Anti-arrhythmic medication (example); DRUG/Antibiotic/Antimicrobial drugs (category); DRUG/Antimalarial medications (examples); DRUG/Breast milk secretion/Danger; DRUG/Cardiovascular meds (examples); DRUG/Class I antiarrhythmic drug (example); DRUG/Class IA antiarrhythmic agent (example); DRUG/Class one/sodium channel myocardial blocker (example); DRUG/Dangerous for kids (10Kg)/Very; DRUG/First dose caution; DRUG/metabolized by CYP 3A pathway; DRUG/Narrow range of safety (effect/toxic); DRUG/Older medication/little used; DRUG/Proarrhythmic drug effect (example); DRUG/Safe in pregnancy patient (B); DRUG/Sodium-channel block effect/toxicity; DRUG/Specialized usage (example)
Pathophysiology: Pathophysiology/Hemolysis
Process: PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin: TOXIN/Hypotension relative bradycardia; TOXIN/Lethal possible

Synonyms
Synonym: Brand name/Cardioquin (Quinidine); Brand name/Quinaglute (Quinidine); Brand name/Quinalan (Quinidine) gluconate; Brand name/Quinate (Quinidine) gluconate; Brand name/Quinidex (Quinidine) sulfate; Brand name/Quinora (Quinidine) sulfate

Treatment
Drug Therapy - Contraindication: RX/Digoxin (Lanoxin); RX/Itraconazole (Sporonox); RX/Warfarin (Coumadin)
Drug Dosage: DRUG/Dose 200 mgms (Unit/Pill/Capsule size); DRUG/Dose 300 mgm (Unit/Pill/Capsule size); DRUG/Dose 324 mgms (Unit/Pill/Capsule size); DRUG/Dose 400 mgm (Unit/Pill/Capsule size); DRUG/Dose Extended time release/XT/SA (example); DRUG/Generic available; DRUG/Oral medication (ex)

Clinical Manifestations
Signs & Symptoms: Chronic Diarrhea in a Child; Diarrhea; Diarrhea and Weight Loss; Diarrhea in Children; Diarrhea, chronic; Failure to Thrive; Fatty food intolerance; Fatty stools/Fecal fat /Greasy stool; Flatus/gas foul smelling; Foul stool; Stool Bulky/greasy/frothy/malodorous; Absent deep tendon reflexes; Absent knee reflexes; Ankle reflexes absent; Areflexia; Ataxia; Awkward Uncoordinated Child; Babinski's upgoing toes/bilateral; Coordination/signs; Limb ataxia/clumsiness child; Mental Deficiency Child; Progressive neurological disorder/signs; Staggering Gait; Symmetric Polyneuropathy; Unable to tandem walk/straight line; Unsteadiness movement/Gait in a child; Walking difficulties; Weight Loss; Color blindness acquired/dimming; Vision Loss
Disease Progression: Course/Chronic disorder; Course/Chronic only; Onset/Infancy

Demographics & Risk Factors
Population Group: Child; Population/Pediatrics population
Sex & Age Groups: Population/Child; Population/Child-Infant Only; Population/Children/all; Population/Preschool child/boy

Laboratory Tests
Microbiology & Serology Findings: Reticulocytosis
Abnormal Lab Findings (Non Measured): Acanthocytes peripheral smear (Lab); Burr cells on smear (Lab); RBC smear/spiny projections/membrane (Lab)
Abnormal Lab Findings - Decreased: Carotene/Vitamin A level (Lab); Cholesterol (Lab); Chylomicrons (Lab); Folic acid/Folate (Lab); Free fatty acids/FFA/Non-esterified (Lab); LDL (Low density lipoprotein) (Lab); Phospholipids, serum (Lab); Sed Rate/ESR/Sedimentation rate (Lab); Triglycerides (Lab); Vitamin E (Tocopherol) (Lab); VLDL (very-low-density lipoprotein) (Lab)
Abnormal Lab Findings - Increased: Anisocytosis (Lab); MCV/Mean Corpuscular Volume (Lab); Poikilocytes (Lab); Polychrome RBCs (Lab); Postprandial lipemia absence; Reticulocytes (Lab); URINE Protein (Albumin); STOOL Fat Sudan stain

Diagnostic Test Results
Pathology: BX/Intestinal biopsy/Jejunal/Abnormal; BX/Intestinal biopsy/Lipid droplets/mucosal cells

Associated Diseases & Rule outs
Associated Disease & Complications - Rule Outs: Ataxia-telangiectasia; Friedreich's Ataxia; Non-alcoholic fatty liver disease; Whipple's disease
Associated Disease & Complications - Causes: Abetalipoproteinemia; Acanthocytosis; Blindness in Children; Cerebellar ataxia; Eales disease/recurrent retinal phlebitis; Fat-soluble vitamin deficiencies (A,D,E,K); Hereditary Blindness; Kyphoscoliosis; Lateral scoliosis/Rotosclerosis; Malabsorption/Steatorrhea syndrome; Mental retardation; Neurodevelopmental disorders; Peripheral neuropathy; Pes cavus/High Arched Foot; Protein losing enteropathy; Proteinuria; Retinitis pigmentosa; Scoliosis; Steatohepatitis; Steatorrhea; Thyrotoxic periodic paralysis; Visual acuity loss; Vitamin A deficiency/Avitaminosis A; Vitamin E deficiency; Polyneuropathy; Proteinuria in Children

Disease Mechanism & Classification
Class: CLASS/Pediatric disorders (ex)
Pathophysiology: Pathophysiology/Beta-lipoprotein absence; Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations); Pathophysiology/Lipid metabolism defect; Pathophysiology/Fat Malabsorption; Pathophysiology/Fat soluble Vitamin Malabsorption; Pathophysiology/Intestine epithelial cell transport defect; Pathophysiology/Malabsorption; Pathophysiology/Hereditary Neuropathy; Pathophysiology/Inherited Biochemical Neuropathy; Pathophysiology/MTTP Gene Mutation
Process: PROCESS/Autosomal recessive disorder (ex); PROCESS/Enzyme defect/Metabolic disorder (ex); PROCESS/Fat soluble vitamin deficiencies (ex); PROCESS/Hereditofamilial (category); PROCESS/INCIDENCE/Rare disease (ex); PROCESS/Metabolic/storage disorder (category); PROCESS/Storage disorder (ex); PROCESS/Developmental degenerative neurological disorder (ex)

Synonyms
Synonym: Synonym/Acanthocytosis, familial; Synonym/Bassen-Kornzweig syndrome; Synonym/LDL deficiency, familial

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