Differential Diagnosis For Reticulocytosis

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  Reticulocytosis

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Trauma Causes

Puerperal hemorrhage/tears/lacerations

Electromagnetic, Physics, trauma, Radiation Causes

Burns/severe/extensive

Surgical, Procedure Complication

Bleeding complications/Surgery

Infectious Disorders (Specific Agent)

Hepatitis, viral

Leptospirosis/severe (Weils) type

Hemolysis with viral infection

Leptospiral disease

Babesiosis

Chronic malaria

Malaria

Leptospirosis Ictohemorrhagica

Infected organ, Abscesses

Hemolytic anemia of infection/acute

Neoplastic Disorders

Colon polyp (adenoma, benign)

Hodgkin's disease

Metastatic bone marrow

Monocytic leukemia, acute

Carcinoma, bone marrow metastasis

Myelogenous leukemia, chronic

Polycythemia vera

Primary Myelofibrosis/Myeloid metaplasia

Atrial myxoma

Erythropoetin producing tumor

Allergic, Collagen, Auto-Immune Disorders

Hemolytic disease of newborn

Hemolytic anemia, autoimmune

HELLP syndrome of pregnancy

Anemia, cryopathic autoimmune

Cold autoimmune hemolytic anemia

Evan's syndrome (AHA/Immune TP)

Paroxysmal Cold Hemoglobinuria

Atypical Hemolytic Uremic Syndrome

Metabolic, Storage Disorders

Glucose 6 PD deficiency

Abetalipoproteinemia (Bassen Kornzweig)

Phosphoglycerate Kinase Deficiency/Systemic homozygous PGKD

Anemia due to glutathione metab def

Wilsons Disease

Gaucher's disease

Phosphofructokinase def/GSD VII (Tarui)

Deficiency Disorders

Vitamin E defic. in newborns

Vitamin E deficiency

Congenital, Developmental Disorders

Congenital disorders

Anemia, congenital hemolytic

Congenital cyanotic heart disease

Meckel diverticulum/Peptic ulcer

Congenital clubbing, digital

Congenital dyserythropoetic anemia

Hereditary, Familial, Genetic Disorders

Sickle cell crisis

Sickle cell/thalassemia disease

Thalassemia major

Thalassemia minor

Spherocytosis, crisis phase

Pyruvate kinase deficiency RBC's

Sickle cell anemia

Sickle cell-hemoglobin D disease

Spherocytosis, hereditary

Hemoglobin H disease

Elliptocytosis, hereditary

Hemoglobin S/C disease

Anemia, hereditary hemolytic,nonspher'c

Thalassemia-hemoglobin C disease

Anatomic, Foreign Body, Structural Disorders

Gastrointestinal bleeding

Uterus, hemorrhage, postpartum

Exsanguinating hemorrhage

Hemorrhage, acute

Internal bleeding/trauma

Lower GI bleeding

Peptic ulcer hemorrhage

Postpartum hemorrhage

Upper GI bleeding

Uterine hemorrhage

Peritoneal bleeding/hemorrhage

Massive intraperitonael hemorrhage

Vegetative, Autonomic, Endocrine Disorders

Erythropoetin, autonomous production

Reference to Organ System

Disseminated intravascular coagulopathy

Anemia, blood loss

Chronic blood loss

Cerebral thrombotic thrombocytopenia

Hemolysis acute

Myelophthisic anemia

Hemolysis process

Hemolysis/non-immune

Hemolytic-uremic syndrome

Paroxysmal Nocturnal Hemoglobinuria

Thrombotic thrombocytopenic purpura

Hypersplenism

Spherocytosis, acquired

Hemolytic Anemia

Pathophysiologic

Anemia, under therapy

Myeloid metaplasia pathophysiology

Drugs

Hydrazine Sulfate Administration/Toxicity

Drug induced Hemolysis

Poisoning (Specific Agent)

Fava-bean hemolysis (G6PD RBC defect)

Arsine gas (Hydrogen arsenide) poisoning

Copper salts exposure/Copper toxicity

Copper sulfate poisoning

Lead poisoning

Arsenic poisoning/Acute ingestion

Organ Poisoning (Intoxication)

Anemia, hemolytic, toxic

Anemia, hemolytic chemical, acquired

Definition

Increase in reticulocyte percentage or absolute reticulocyte count in blood beyond normal for age; Reticulocytes are young red cells just after the nucleus is removed; high percent in red cell destruction disorders and low percent in bone marrow depression or deficiency diseases such as iron deficiency.

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NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)