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Differential Diagnosis For Macrocytic anemia (Lab)


List of current finding(s):

Surgical, Procedure Complication
Ileum resection
Terminal ileum surgical resection
Afferent loop/Bilroth II surgery effect
Blind-loop syndrome
Short-bowel syndrome
Infectious Disorders (Specific Agent)
Diphyllobothrium latum infestation
Sprue, tropical
Whipples disease
Neoplastic Disorders
Blood dyscrasia
Carcinoma, bone marrow metastasis
Erythroleukemia/DiGuglielmo's syndrome
Myelodysplasia Myelodysplastic Syndrome
Primary Myelofibrosis/Myeloid metaplasia
Allergic, Collagen, Auto-Immune Disorders
Hemolytic anemia, autoimmune
Metabolic, Storage Disorders
Neonatal hyperbilirubinemia
Impaired folic acid metabolism
Orotic aciduria, hereditary
Dihydrofolate reductase deficiency
Lesch-Nyhan syndrome
Transcobalamin II deficiency
Deficiency Disorders
Folate depletion
Folic acid deficiency anemia
Inadequate B12 intake
Inadequate Folic acid in diet
Folic acid dependency/metabolic defect
Kwashiorkor (protein deficiency,severe)
Malabsorption of B12
Malabsorption of folic acid
Pellagra/niacin deficiency
Vitamin B12 deficiency
Congenital, Developmental Disorders
B12 Malabsorption, selective, congen.
Congenital dyserythropoetic anemia
Congenital intrinsic factor absence
Folate malabsorption, congenital
Functional, Physiologic Variant Disorders
Diet, strict vegetarian
Pregnancy, 3rd trimester
Recent blood donation/Phlebotomy
Vegetative, Autonomic, Endocrine Disorders
Hypothyroidism (myxedema)
Hypothyroidism, juvenile
Reference to Organ System
Liver disease/Liver disorders
Anemia, blood loss
Anemia, megaloblastic of pregnancy
Chronic liver disease
Malabsorption syndrome
Megaloblastic anemia
Pernicious anemia
Refractory anemia, primary (idiopathic)
Combined system disease/pernicious an.
Refractory megaloblastic anemia
Increased folic acid requirements
Malabsorption pathophysiology
Myeloid metaplasia pathophysiology
Heirarchical Major Groups
Terminal ileum disorders
Methotrexate (Rheumatrex) Administration/Toxicity
Phenytoin (Dilantin) Administration/Toxicity
Zidovudine (Retrovir/AZT)Azidothymidine
Poisoning (Specific Agent)
Alcohol debauche (binge)
Alcoholic fatty liver
Alcoholic liver disease
Alcoholism, chronic
Hepatitis, alcoholic
Fetal alcohol syndrome
Anaemia macrocytic, ANEMIA MACROCYTIC, Anemias Macrocytic, Lab, macrocytic anaemia, Macrocytic anaemia of unspecified cause, Macrocytic anaemia -unsp cause, Macrocytic Anemia, Macrocytic anemia (disorder), Macrocytic anemia of unspecified cause, Macrocytic anemia of unspecified cause (disorder), Macrocytic anemia -unsp cause, Macrocytic Anemias

Macrocytic anemia is the increase in MCV( mean corpuscular volume), MCV> 96fL. It can be due to deficiency of vitamin B12 or folate and several other conditions. Reticulocytosis can increase MCV.


External Links Related to Macrocytic anemia (Lab)
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)