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Differential Diagnosis For Low WBC/Left shift/Low platelets (Lab)


List of current finding(s):

Infectious Disorders (Specific Agent)
Typhus, acute/epidemic
Lassa fever
Rickettsial disease
Rocky mountain spotted fever
Q fever
Typhus, murine
Neoplastic Disorders
Primary Myelofibrosis/Myeloid metaplasia
Allergic, Collagen, Auto-Immune Disorders
Lupus erythematosis, systemic
Reference to Organ System
Disseminated intravascular coagulopathy
Myelophthisic anemia
Poisoning (Specific Agent)
Alcoholic ketoacidosis
Hepatitis, alcoholic
blood platelets decreased, decreased blood platelets, Decreased platelet count, Decreased platelets, Decreased white blood cell count, Decreased white cell count, IMMATURE LEUKOCYTES INCREASED, Lab, LEFT SHIFT, Left shift leukocytic maturation alteration, Left shift of WBC, Left shifted white blood cells, Left shifted white blood cells (finding), Leukocyte count decreased, leukocytes decreased, Leukocytes.left shift, Leukocytic maturation alteration left shift, Low platelets, Platelet count decreased, Platelet count low, platelets decreased, platelets low, Reduced platelet count, Shift to the left, Shift to the left (haematological), Shift to the left (hematological), Thrombocyte count decreased, WBC DEC, WBC DECREASED, WBC LEFT SHIFT, WBC LOW, WHITE BLOOD CELL COUNT DECREASED, White blood cell decreased, WHITE BLOOD CELLS DECREASED

high wbc/ left shift

Increased neutrophil count

An increased need for neutrophils, as with an acute bacterial infection, will cause an increase in both the total number of mature neutrophils and the less mature bands or stabs to respond to the infection. The term "shift to the left" is often used when determining if a patient has an inflammatory process such as acute appendicitis or cholecystitis. This term is a holdover from days in which lab reports were written by hand. Bands or stabs, the less mature neutrophil forms, were written first on the left-hand side of the laboratory report. Today, the term "shift to the left" means that the bands or stabs have increased, indicating an infection in progress.

For example, a patient with acute appendicitis might have a "WBC count of 15,000 with 65% of the cells being mature neutrophils and an increase in stabs or band cells to 10%". This report is typical of a "shift to the left", and will be taken into consideration along with history and physical findings, to determine how the patient's appendicitis will be treated.

Low platelets combined with high WBC and Left shift to younger neutrophiles defines a new differential diagnosis cause list.


External Links Related to Low WBC/Left shift/Low platelets (Lab)
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)